Evidence map›Paper›PMID 40661525›Full record

ArticlebioRxiv : the preprint server for biology2025

Observing intersubunit dynamics in single yeast ribosomes.

Ananya Das, Aleksandr V Ivanov, Hironao Wakabayashi, Amy K Grove, Dmitri N Ermolenko

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ananya DasDepartment of Biochemistry & Biophysics, School of Medicine and Dentistry, and Center for RNA Biology, University of Rochester, Rochester, NY 14642.
Aleksandr V IvanovDepartment of Biochemistry & Biophysics, School of Medicine and Dentistry, and Center for RNA Biology, University of Rochester, Rochester, NY 14642.
Hironao WakabayashiDepartment of Biochemistry & Biophysics, School of Medicine and Dentistry, and Center for RNA Biology, University of Rochester, Rochester, NY 14642.
Amy K GroveDepartment of Biochemistry & Biophysics, School of Medicine and Dentistry, and Center for RNA Biology, University of Rochester, Rochester, NY 14642.
Dmitri N ErmolenkoDepartment of Biochemistry & Biophysics, School of Medicine and Dentistry, and Center for RNA Biology, University of Rochester, Rochester, NY 14642.ORCID 0000-0002-7554-5967

Funding

Structural Dynamics of TranslationR35GM141812 · NIGMS · UNIVERSITY OF ROCHESTER · PI ERMOLENKO, DMITRI · 2021 to 2025
$2.8M
Acquisition of a Typhoon FLA 9500 Laser Scanning ImagerS10OD021489 · OD · UNIVERSITY OF ROCHESTER · PI BUTLER, JAMES SCOTT · 2017 to 2017
$130k
NIGMS NIH HHS R35 GM141812NIH HHS S10 OD021489
6 · The paper itself

Abstract

Translation is accompanied by rotation of the small and large ribosomal subunits relative to each other. Here, we use single-molecule Förster resonance energy transfer between fluorophores introduced into ribosomal proteins uS15 and eL30 to follow intersubunit dynamics of

Identifiers

PMID40661525
PMCPMC12258932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.