Evidence map›Paper›PMID 40661508›Full record

ArticlebioRxiv : the preprint server for biology2025

Filopodia numbers impact chemotactic migration speed.

Annika L Schroder, Livia D Songster, Yahor Savich, Margaret A Titus

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Annika L SchroderDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.
Livia D SongsterDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.ORCID 0000-0002-2395-4224
Yahor SavichDepartment of Biochemistry, Molecular Biology, and Biophysics and School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455.
Margaret A TitusDepartment of Genetics, Cell Biology, and Development, University of Minnesota, Minneapolis, MN 55455.

Funding

Mechanism of myosin motor-dependent filopodia formationR01GM122917 · NIGMS · UNIVERSITY OF MINNESOTA · PI TITUS, MARGARET A · 2017 to 2024
$3.2M
NIGMS NIH HHS R01 GM122917
6 · The paper itself

Abstract

Migrating cells sense and respond to external chemical and physical cues, enabling them to efficiently reach their destinations. Filopodia are slender actin-filled membrane protrusions implicated in interacting with the extracellular environment in many contexts, such as neuronal growth cone guidance and the capture of prey by immune cells and unicellular organisms. The role of filopodia in chemotactic guidance in fast-moving amoeboid cells has not been well-studied. The social amoeba

Indexed as

actinamoeboid migrationchemotaxisdirected migrationfilopodiamyosin

Identifiers

PMID40661508
PMCPMC12258711

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.