Evidence map›Paper›PMID 40661497›Full record

ArticlebioRxiv : the preprint server for biology2025

Impaired envelope integrity in the absence of SanA is linked to increased Lipid II availability and an imbalance of FtsI and FtsW activities.

Joseph F Carr, Carolina Basurto De Santiago, Shivani A Bhut, Daniel J Warzecha, Robert Wei, Carmen M Herrera, M Stephen Trent, Beiyan Nan, Angela M Mitchell

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Joseph F CarrDepartment of Biology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0001-9228-8168
Carolina Basurto De SantiagoDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Shivani A BhutDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Daniel J WarzechaDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Robert WeiDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Carmen M HerreraDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
M Stephen TrentDepartment of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
Beiyan NanDepartment of Biology, Texas A&M University, College Station, Texas, USA.
Angela M MitchellDepartment of Biology, Texas A&M University, College Station, Texas, USA.ORCID 0000-0003-1062-0716

Funding

Biogenesis of cyclic and phospholipid-linked enterobacterial common antigenR01AI155915 · NIAID · TEXAS A&M UNIVERSITY · PI MITCHELL, ANGELA MARIE · 2021 to 2025
$2.0M
The Origin of Rod Shape in BacteriaR01GM129000 · NIGMS · TEXAS A&M UNIVERSITY · PI NAN, BEIYAN · 2018 to 2022
$1.6M
NIAID NIH HHS R01 AI155915NIGMS NIH HHS R01 GM129000
6 · The paper itself

Abstract

In gram-negative bacteria, the outer membrane (OM) acts in conjunction with the peptidoglycan (PG) cell wall as a barrier against physical, osmotic, and toxic environmental stresses including antibiotics. SanA, an inner membrane protein in

Identifiers

PMID40661497
PMCPMC12259093

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.