ArticlebioRxiv : the preprint server for biology2025
Single-cell multiomics identifies both shared and unique features of immune dysfunction in Parkinson's disease and inflammatory bowel disease colon, plasma and stool.
MacKenzie L Bolen, Marc Buendia, Ji Shi, Hannah Staley, Jennifer M Kachergus, Philip A Efron, Gwoncheol Park, Ravinder Nagpal, Stephan D Alvarez, Qing-Shan Xue and 7 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
17 authors.
MacKenzie L BolenCenter for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0003-1973-3784 Ji ShiAugust Pi i Sunyer Biomedical Research Institute (IDIBAPS), Barcelona, CIBER-EHD, Spain.
Hannah StaleyCenter for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0009-0001-8284-6178 Jennifer M KachergusDepartment of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Philip A EfronDepartment of Surgery, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-3931-650X Gwoncheol ParkThe Gut Biome Lab, Department of Health, Nutrition, and Food Sciences, College of Education, Health, and Human Sciences, Florida State University, Tallahassee, FL, USA.ORCID 0000-0003-3778-5895 Ravinder NagpalThe Gut Biome Lab, Department of Health, Nutrition, and Food Sciences, College of Education, Health, and Human Sciences, Florida State University, Tallahassee, FL, USA.ORCID 0000-0002-4250-1749 Stephan D AlvarezNorman Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.ORCID 0009-0000-4420-7394 Qing-Shan XueCenter for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.
Nikolaus R McFarlandDepartment of Neurology, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-8699-8857 Ellen M ZimmermannDepartment of Medicine, Division of Gastroenterology, College of Medicine, University of Florida, Gainesville, FL, USA.
Christopher E ForsmarkDepartment of Medicine, Division of Gastroenterology, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-2508-1543 Kelly B MeneesCenter for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0003-4282-8546 Azucena SalasUniversity of Barcelona.
E Aubrey ThompsonDepartment of Cancer Biology, Mayo Clinic, Jacksonville, FL, USA.
Malú Gámez TanseyCenter for Translational Research in Neurodegenerative Disease, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-1719-4708 Funding
Role of central and peripheral immune crosstalk in FTD-Grn neurodegenerationRF1NS128800 · NINDS · UNIVERSITY OF FLORIDA · PI FINKBEINER, STEVEN M, TANSEY, MARIA DE LOURDES GAMEZ · 2022 to 2022
$2.4MR35 Equipment SupplementR35GM140806 · NIGMS · UNIVERSITY OF FLORIDA · PI EFRON, PHILIP A · 2021 to 2025
$2.2MRole of Gut Inflammation and Immunity on Proteostasis, Noradrenergic Degeneration and AD riskRF1AG057247 · NIA · UNIVERSITY OF FLORIDA · PI NEISH, ANDREW S, TANSEY, MARIA DE LOURDES GAMEZ · 2017 to 2017
$1.6MRole of central and peripheral immune crosstalk in FTD-Grn neurodegenerationR01NS128800 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI STEVEN M FINKBEINER, Maria de Lourdes Gamez Tansey · 2025 to 2026
$1.5MNIA NIH HHS RF1 AG057247NIGMS NIH HHS R35 GM140806NINDS NIH HHS R01 NS128800NINDS NIH HHS RF1 NS128800
6 · The paper itselfAbstract
Parkinson's disease (PD) is the fastest growing neurodegenerative disease in the world
Identifiers
PMID40661410
PMCPMC12258910
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