Evidence map›Paper›PMID 40661361›Full record

ArticlebioRxiv : the preprint server for biology2025

Structure of the conjugation surface exclusion protein TraT.

Nicolas Chen, Alfredas Bukys, Camilla A K Lundgren, Justin C Deme, Hafez El Sayyed, Achillefs N Kapanidis, Susan M Lea, Ben C Berks

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Nicolas ChenDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom.ORCID 0009-0007-2421-8468
Alfredas BukysDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom.ORCID 0009-0007-9250-9005
Camilla A K LundgrenDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom.ORCID 0000-0001-8854-6937
Justin C DemeCenter for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, United States of America.ORCID 0000-0001-8811-9871
Hafez El SayyedBiological Physics Research Group, Department of Physics, University of Oxford, Oxford OX1 3PU, United Kingdom.
Achillefs N KapanidisBiological Physics Research Group, Department of Physics, University of Oxford, Oxford OX1 3PU, United Kingdom.ORCID 0000-0002-0904-5323
Susan M LeaCenter for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD 21702, United States of America.ORCID 0000-0001-9287-8053
Ben C BerksDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom.ORCID 0000-0001-9685-4067

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Conjugal transfer of plasmids between bacteria is a major route for the spread of antimicrobial resistance. Many conjugative plasmids encode exclusion systems that inhibit redundant conjugation. In incompatibility group F (IncF) plasmids surface exclusion is mediated by the outer membrane protein TraT. Here we report the cryoEM structure of the TraT exclusion protein complex from the canonical F plasmid of

Identifiers

PMID40661361
PMCPMC12258729

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.