Evidence map›Paper›PMID 40661282›Full record

ArticlemedRxiv : the preprint server for health sciences2025

The Re-emergence of Chikungunya in Sri Lanka: A Genomic investigation.

Tibutius Thanesh Pramanayagam Jayadas, Malithi de Silva, Bhagya Senadheera, Laksiri Gomes, Heshan Kuruppu, Radanee Rathnapriya, Farha Bary, Sahan Madusanka, Ananda Wijewickrama, Damayanthi Idampitiya and 4 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tibutius Thanesh Pramanayagam JayadasInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Malithi de SilvaInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Bhagya SenadheeraInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Laksiri GomesInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Heshan KuruppuInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Radanee RathnapriyaInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Farha BaryInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Sahan MadusankaInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Ananda WijewickramaNational Institute of Infectious Diseases, Angoda, Sri Lanka.
Damayanthi IdampitiyaNational Institute of Infectious Diseases, Angoda, Sri Lanka.
Suranga ManilgamaNational Institute of Infectious Diseases, Angoda, Sri Lanka.
Ruklanthi de AlwisProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Chandima JeewandaraInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.
Gathsaurie Neelika MalavigeInstitute of Allergology and Immunology, University of Sri Jayewardenepura, Gangodawila, Nugegoda, Sri Lanka.

Funding

American Asian Centers for Arbovirus Research and Enhanced Surveillance (A2CARES)U01AI151788 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Josefina Coloma, Eva Harris · 2020 to 2026
$9.6M
NIAID NIH HHS U01 AI151788
6 · The paper itself

Abstract

Sri Lanka is currently experiencing a large Chikungunya outbreak, since the end of 2024, after 16 years. We carried out whole genomic sequencing of the currently circulating Chikungunya virus (CHIKV) strain and found that it was of the Indian ocean lineage (IOL), similar to the currently circulating CHIKV strains in South Asia. While the E:226V mutation, which has been associated with

Indexed as

Chikungunya virusIndian-ocean lineagemolecular epidemiologymutationsoutbreaksequencing

Identifiers

PMID40661282
PMCPMC12258780

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.