ArticleJournal of pain research2025
Association Between Opioid Use and Emergency Department Visits for Spine-Related Disorders.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Pain severity and opioid use in patients with spine-related diagnoses.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Opioids are frequently prescribed to patients with spine-related disorders (SRD), including those undergoing spinal surgery and those with various back or neck pain. Previous studies assessing the association between opioid use and the risk of emergency department (ED) visits among SRD patients have been limited to specific patient subgroups. Using nationally representative sample, we estimated the association between opioid use and the frequency of all-cause ED visits among SRD patients in the United States. Methods: This was a retrospective cross-sectional study design that utilized 2018-2022 Medical Expenditure Panel Survey (MEPS) data. Patients with SRD were identified using ICD-10-CM codes matching for spine-related diagnoses. The primary exposure variable was opioid use, defined by the MEPS prescription drug file. The outcome was all-cause ED visits, which were measured as the number of ED visits observed between 2018 and 2022 as reported in the MEPS emergency room visits files. Descriptive weighted analyses were used to examine the characteristics of patients with SRD. We selected the zero-inflated negative binomial model, which had the best model fit based on the Akaike Information Criterion (AIC), to estimate the incident rate ratio of all-cause ED visits for opioid users compared to non-opioid users. Results: The final sample consisted of 8078 adult patients (18632323 weighted sample) with SRD diagnoses, among whom approximately 21% received opioid prescriptions. The proportion of opioid users compared to non-opioid users varied by gender (opioid users: male 39.34%, female 60.66%; non-opioid users: male 42.45%, female 57.55%; P = 0.045) and insurance type (opioid users: private 61.51%, public 36.92%, uninsured 1.57%; non-opioid users: private 69.87%, public 26.49%, uninsured 3.64%; P < 0.001). Multivariable analysis revealed a significant association between opioid use and increased ED visits (IRR= 1.63, 95% CI: 1.39-1.90). Conclusion: We found that opioid use significantly increases the frequency of all-cause ED visits among SRD patients. These findings highlight the importance of cautious opioid prescribing among SRD patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.