Evidence map›Paper›PMID 40661206›Full record

ArticleRSC advances2025

A short amphipathic peptide-based injectable hydrogel with antibacterial properties.

Dorien Aerssens, Atiruj Theppawong, Hue Vu, Petra Rigole, Marleen Van Troys, Tom Coenye, Richard Hoogenboom, Steven Ballet, Charlotte Martin, Annemieke Madder

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dorien AerssensOrganic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University 9000 Ghent Belgium annemieke.madder@ugent.be.
Atiruj TheppawongOrganic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University 9000 Ghent Belgium annemieke.madder@ugent.be.
Hue VuOrganic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University 9000 Ghent Belgium annemieke.madder@ugent.be.
Petra RigoleDepartment of Pharmaceutical Analysis, Ghent University 9000 Ghent Belgium.
Marleen Van TroysDepartment of Biomolecular Medicine, Ghent University 9000 Ghent Belgium.ORCID https://orcid.org/0000-0003-4283-8103
Tom CoenyeDepartment of Pharmaceutical Analysis, Ghent University 9000 Ghent Belgium.
Richard HoogenboomSupramolecular Chemistry Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University 9000 Ghent Belgium.ORCID https://orcid.org/0000-0001-7398-2058
Steven BalletResearch Group of Organic Chemistry, Vrije Universiteit Brussel B-1050 Brussels Belgium.ORCID https://orcid.org/0000-0003-4123-1641
Charlotte MartinResearch Group of Organic Chemistry, Vrije Universiteit Brussel B-1050 Brussels Belgium.
Annemieke MadderOrganic and Biomimetic Chemistry Research Group, Department of Organic and Macromolecular Chemistry, Ghent University 9000 Ghent Belgium annemieke.madder@ugent.be.ORCID https://orcid.org/0000-0003-0179-7608

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogel materials have gained considerable interest to be used as aids in the healing of chronic and traumatic wounds, in view of their tunable mechanical stability, biocompatibility and biodegradability. Here, we describe the development of a new injectable and antibacterial peptide-based hydrogel that is composed of only nine natural amino acids. By covalently merging a short antibacterial peptide sequence with a short hydrogelator peptide sequence, the biologically active sequence H-RWRWQFQFK-NH

Identifiers

PMID40661206
PMCPMC12257300

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.