Evidence map›Paper›PMID 40661143›Full record

Article3 Biotech2025

Anti-bacterial activity of silibinin-functionalized silica-coated Fe

Nazanin Pasandideh Kordmahaleh, Mirsasan Mipour, Najmeh Ranji, Mahdi Shahriarinour, Mohammad Nikpassand

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in 3 Biotech, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Preparation of silibinin- dendrimer-stabilized Au nanoparticles for decreasing vancomycin resistance in S. aureus clinical isolates.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nazanin Pasandideh KordmahalehDepartment of Microbiology, La. C., Islamic Azad University (IAU), Lahijan, Guilan Iran.
Mirsasan MipourDepartment of Microbiology, La. C., Islamic Azad University (IAU), Lahijan, Guilan Iran.ORCID 0000-0001-7641-462X
Najmeh RanjiDepartment of Biology, Ra. C., Islamic Azad University (IAU), Rasht, Guilan Iran.ORCID 0000-0001-5233-2427
Mahdi ShahriarinourDepartment of Biology, Ra. C., Islamic Azad University (IAU), Rasht, Guilan Iran.ORCID 0000-0002-4596-591X
Mohammad NikpassandDepartment of Biology, Ra. C., Islamic Azad University (IAU), Rasht, Guilan Iran.ORCID 0000-0002-9692-6849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nanocomposites were synthesized and characterized using Fourier transform infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM), and X-ray diffraction (XRD). The physicochemical analyses confirmed the structural integrity, uniform particle size (34-58 nm), thermal stability (> 600 °C), and magnetic properties of the nanocomposites. The nanocomposites exhibited strong synergistic effects with ciprofloxacin, reducing the minimum inhibitory concentration (MIC) in combination by 4- to 16-fold compared to ciprofloxacin alone. Furthermore, the nanocomposites in combination with ciprofloxacin significantly inhibited biofilm formation in clinical isolates. The gene expression analysis revealed downregulation of key efflux pump genes (

Indexed as

BiofilmPseudomonas aeruginosaQuantitative real time-PCRSilibininSilica-coated magnetic nanoparticles

Identifiers

PMID40661143
PMCPMC12255613

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.