Evidence map›Paper›PMID 40661094›Full record

ArticleEplasty2025

Piscine-Derived Acellular Dermal Matrix in Upper Extremity Reconstruction.

Shawhin Shahriari, Cees Whisonant, Joseph Kuhn, Tyler Chavez, Joshua Harrison, Casey McDonald, Adam Schwartz, Jolee Suddock, Elizabeth Mikola, Gregory Borah

Abstract read
In one paragraph

Article in Eplasty, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Dermal Scaffolds in Complex Extremity Wound Reconstruction: Impact of Early Application on Grafting and Flap Requirements-A Systematic Review.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Pooled it
  2. Article
  3. Fish Acellular Dermal Matrix Promotes Repair of Full-Thickness Skin Defects in Mice and Bama Pigs.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shawhin ShahriariUniversity of New Mexico, Department of Surgery, Division of Plastic, Reconstructive, Hand and Burn Surgery, Albuquerque, New Mexico.
Cees WhisonantCreighton University - Phoenix, Department of Surgery, Phoenix, Arizona.
Joseph KuhnUniversity of New Mexico, Department of Surgery, Division of Plastic, Reconstructive, Hand and Burn Surgery, Albuquerque, New Mexico.
Tyler ChavezUniversity of New Mexico, Department of Orthopaedic Surgery, Albuquerque, New Mexico.
Joshua HarrisonUniversity of New Mexico, Department of Surgery, Division of Plastic, Reconstructive, Hand and Burn Surgery, Albuquerque, New Mexico.
Casey McDonaldUniversity of Texas Health - San Antonio, Department of Orthopaedics, San Antonio Texas.
Adam SchwartzUniversity of New Mexico, Department of Surgery, Division of Plastic, Reconstructive, Hand and Burn Surgery, Albuquerque, New Mexico.
Jolee SuddockUniversity of New Mexico, Department of Pathology, Albuquerque, New Mexico.
Elizabeth MikolaUniversity of New Mexico, Department of Orthopaedic Surgery, Albuquerque, New Mexico.
Gregory BorahUniversity of New Mexico, Department of Surgery, Division of Plastic, Reconstructive, Hand and Burn Surgery, Albuquerque, New Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Wound reconstruction involving exposed critical structures, especially in medically complex patients and in those who are at high risk of loss to follow-up, presents a unique challenge to surgeons. The use of acellular dermal matrix (ADM) has augmented our ability to address these wounds safely and with minimal morbidity. A piscine ADM, the Kerecis Omega3 Wound, has shown promise in the treatment of chronic wounds and burns. In this study, we describe the use of the Omega3 Wound in reconstruction of upper extremity wounds, including those with exposed critical structures. Methods: From 2019 to 2021, 11 consecutive patients with upper extremity wounds, including 9 with exposed critical structures, were queried. Clinical data was tabulated to evaluate outcomes. Results: Etiology of the wounds included burns, trauma, infection, and oncologic resection. Wound surface area was 150 ± 42 cm Conclusions: The Omega3 Wound allows for complete biologic integration and vascularized wound coverage that accepts a skin graft. Patients can be discharged after application and managed at outpatient facilities. This ADM is safe and well tolerated by patients (including those who are diabetic and immunocompromised) for coverage of upper extremity wounds with exposed critical structures.

Indexed as

Acellular Dermal MatrixFish SkinKerecisLimb SalvageUpper Extremity Salvage

Identifiers

PMID40661094
PMCPMC12257959

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.