Evidence map›Paper›PMID 40661073›Full record

ReviewFrontiers in pharmacology2025

Integrative approaches in Alzheimer's disease: evaluating the potential of traditional, complementary, and integrative medicine (TCIM).

R Sneha Sri, T Pavithra, T Vinciya, V Santhosh Kumar, N Harikrishnan, Rukaiah Fatma Begum, S Ankul Singh

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Investigation of the Potential Neuroprotective Mechanisms ofInternational journal of molecular sciences · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

R Sneha SriDepartment of Pharmacology, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
T PavithraDepartment of Pharmacology, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
T VinciyaDepartment of Pharmacology, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
V Santhosh KumarDepartment of Pharmacology, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
N HarikrishnanDepartment of Pharmaceutical Analysis, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
Rukaiah Fatma BegumInstitute of Pharmaceutical Research, GLA University, Mathura, Uttar Pradesh, India.
S Ankul SinghDepartment of Pharmacology, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review explores the potential of Traditional, Complementary, and Integrative Medicine (TCIM) as an adjunct to conventional therapies for Alzheimer's Disease (AD). Unlike pharmaceutical treatments that primarily offer symptomatic relief, TCIM encompasses holistic approaches that target multiple pathophysiological pathways involved in AD, including tau pathology, oxidative stress, mitochondrial dysfunction, and neuroinflammation. Herbal therapies such as

Indexed as

Alzheimer’s disease (AD)cognitive declinecomplementary and integrative medicine (TCIM)herbal therapiesneuroinflammationtraditional medicine

Identifiers

PMID40661073
PMCPMC12256855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.