Evidence map›Paper›PMID 40660902›Full record

ArticleJournal of applied clinical medical physics2025

Univariate and multivariate analysis of the styrofoam fixation device on patient setup errors in radiotherapy.

Jun Chen, Yi Guo, Changsheng Wang, Simin Lin, Linglong Shao, Linzhen Lan, Feibao Guo

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07676032 (The Impact of Body Composition on Setup Errors in Patients Undergoing Radiotherapy With Thermoplastic Mask Immobilization), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07676032 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Impact of Body Composition on Setup Errors in Patients Undergoing Radiotherapy With Thermoplastic Mask Immobilization: A Single-Center Prospective Cohort Study

Typeobservational_patient_registrySponsorShijiazhuang People's HospitalRan2026 to 2027Enrolled150ConditionsMalignant Neoplasms
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jun ChenDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Yi GuoDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.ORCID https://orcid.org/0000-0003-0400-2145
Changsheng WangDepartment of Radiology, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Simin LinDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Linglong ShaoDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Linzhen LanDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.
Feibao GuoDepartment of Radiotherapy, Cancer Center, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China.

Funding

Fujian Provincial Health Technology Project 2022GGA025the Leading Project Foundation of Science and Technology, Fujian Province of China 2023Y0017
6 · The paper itself

Abstract

backgroundStyrofoam is a patient-specific immobilization device in radiotherapy; most previous studies about the impact of styrofoam on setup errors have only analyzed a single tumor type, and have not considered the influence of patient's physical condition on the setup errors of styrofoam. PURPOSE: This study aims to evaluate the impact of styrofoam device on setup errors in radiotherapy and explore which patient population is more suitable for styrofoam immobilization.

methodsUnivariate and multivariate analyses were conducted to compare the setup errors between the experimental group (styrofoam combined with thermoplastic mask) and the control group (thermoplastic mask alone). All cases were categorized based on tumor location into head and neck, thorax, abdomen, and limb cases, with age, gender, surgical history, educational level, and body mass index (BMI) serving as variables in the multivariate analysis. Intragroup analysis was also performed.

resultsFor all included cases, the experimental group had median setup errors of 1.20 , 2.00 , and 1.30 mm in the vertical, longitudinal, and lateral directions, respectively. In contrast, the control group had median setup errors of 1.50 , 2.00 , and 1.85 mm in the same respective directions. Notably, the experimental group demonstrated statistically significant reductions in average setup errors in the longitudinal direction (2.00  vs. 2.87 mm, p < 0.01) and lateral direction (1.90  vs. 2.24 mm, p < 0.01) compared to the control group. The intragroup analysis results indicated that factors such as age, gender, surgical history, and educational level had no significant impact on the setup errors in the experimental group.

conclusionThe styrofoam fixation device for patient immobilization can effectively reduce setup errors in both the longitudinal and lateral directions, and the styrofoam fixation device is suitable for most people.

Indexed as

Head and Neck NeoplasmsImmobilizationNeoplasmsPatient PositioningRadiotherapy Planning, Computer-AssistedRadiotherapy Setup ErrorsAdultAgedFemaleHumansMaleMiddle AgedMultivariate AnalysisRadiotherapy DosageRadiotherapy, Intensity-Modulatedradiotherapysetup errorsStyrofoam

Identifiers

PMID40660902
PMCPMC12260254

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.