ReviewJournal of experimental botany2025
CLE pathways in plant development: recent advances and future perspectives.
Review in Journal of experimental botany, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Processing and release of endogenous immunogenic peptide signals.The Plant journal : for cell and molecular biology · 2026Review
- Regulatory layers of robustness of CLAVATA-WUSCHEL feedback system in stem cell homeostasis.Frontiers in plant science · 2026Review
- Peptides: powerful, pervasive, and full of potential.Journal of experimental botany · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
The evolution of land plants was driven by novel genes that enabled adaptation to water and nutrient deficiency and development of a three-dimensional body. The appearance of genes encoding small peptides that move from cell to cell and activate membrane-localized receptors represented an important innovation in early land plants. Among these gene families, the CLAVATA3/EMBRYO-SURROUNDING REGION-RELATED (CLE) genes were particularly crucial for plant developmental control, presumably due to their initial involvement in cell division regulation. Recent advances in understanding the role of CLE signalling in bryophytes and ferns, along with major achievements in identifying the full repertoire of CLE genes in plant genomes and unravelling their functions, have provided deeper insights into these conserved signalling pathways. Here, we provide an update on CLE pathways and their fundamental role in plant development. We also discuss emerging questions in the CLE signalling field that could open exciting research directions and offer a way to manipulate plant morphology and adaptability that will be instrumental for improving crops in the future.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.