Evidence map›Paper›PMID 40660776›Full record

ArticleOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2025

A New Indocyanine Green Lymphography Protocol for Assessment of Lymphedema in the Head and Neck.

Hiroo Suami, Katrina Gaitatzis, Helen Mackie, Belinda Thompson, Fiona T Blake, Dion Forstner, Puma Sundaresan, Roman Skoracki, Louise Koelmeyer

Abstract read
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In one paragraph

Article in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hiroo SuamiAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-4841-3328
Katrina GaitatzisAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6043-712X
Helen MackieAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-9751-319X
Belinda ThompsonAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-7427-9986
Fiona T BlakeAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0009-0005-2606-8411
Dion ForstnerGenesisCare, Macquarie University Hospital, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-6963-6942
Puma SundaresanGenesisCare, Macquarie University Hospital, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9151-0150
Roman SkorackiDepartment of Plastic Surgery, Ohio State University, Columbus, Ohio, USA.ORCID https://orcid.org/0000-0002-0665-2064
Louise KoelmeyerAustralian Lymphoedema Education Research and Treatment Centre (ALERT), Department of Health Sciences, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-2736-2330

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer and its treatment may result in lymphedema, however, no specific imaging criteria have been assigned to diagnose this condition. This study reports an ICG lymphography protocol for investigating changes in individuals experiencing swelling post-neck dissection. ICG lymphography was performed in 10 healthy participants and 16 individuals who complained of facial or neck swelling following treatment for head and neck cancer. Four ICG injection sites were proposed to demonstrate 3 lymphatic territories draininig to upper cervical, submandibular, and submental nodes. In healthy controls, 3 lymphatic drainage pathways were demonstrated in the ipsilateral neck. In individuals post-neck dissection, dermal backflow was present and 2 additional drainage pathways were visualized to the paraspinal and axillary regions. This study proposes an anatomy-based protocol for ICG lymphography and interpretations of imaging findings in patients post-neck dissection surgery. ICG lymphography offers a diagnostic imaging tool for head and neck lymphedema.

Indexed as

Head and Neck NeoplasmsIndocyanine GreenLymphedemaLymphographyNeck DissectionAdultAgedCase-Control StudiesColoring AgentsFemaleHumansMaleMiddle AgedColoring AgentsIndocyanine Greenhead and neck cancerindocyanine greenlymphedemalymphographyneck dissection

Identifiers

PMID40660776
PMCPMC12574634

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.