Evidence map›Paper›PMID 40660699›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2025

Efficacy of Guanfacine for Self-injurious and Aggressive Behaviors through the Reduction of Impulsivity in Borderline Personality Disorder: Two Case Reports and a Literature Review.

Hiroaki Mori, Shinichiro Ochi, Hidetoshi Hashida, Jun-Ichi Iga, Shu-Ichi Ueno

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hiroaki MoriDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Toon, Japan.ORCID https://orcid.org/0009-0007-7097-5216
Shinichiro OchiDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Toon, Japan.ORCID https://orcid.org/0000-0003-2263-3477
Hidetoshi HashidaDepartment of Psychiatry, Shokokai Imabari Hospital, Imabari, Japan.ORCID https://orcid.org/0009-0004-4740-2290
Jun-Ichi IgaDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Toon, Japan.ORCID https://orcid.org/0000-0003-4409-3096
Shu-Ichi UenoDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Toon, Japan.ORCID https://orcid.org/0000-0002-2611-962X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Borderline personality disorder (BPD) is a complex psychiatric disorder characterized by emotional instability, impulsivity, and self-destructive behavior. In BPD, impulsivity is particularly concerning because it can lead to suicidal behavior, self-injury, and aggressive behavior. Guanfacine, an α

Indexed as

Attention deficit disorder with hyperactivityBorderline personality disorderGuanfacineImpulsive behaviorPrefrontal cortex

Identifiers

PMID40660699
PMCPMC12264677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.