Evidence map›Paper›PMID 40660632›Full record

SynthesisPsycho-oncology2025

The Current State of Palliative Care Research for Adolescents and Young Adults With Cancer: A Systematic Review and Meta-Thematic Analysis of Empirical Literature.

Anao Zhang, Meiyan Chen, Rachel Brandon, Jennifer Currin-McCulloch, Xingzhi Liu, Brennan Cheladyn, Betty Ferrell, Barbara Jones, Bradley Zebrack, Adam S DuVall

Abstract readSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anao ZhangUniversity of Michigan School of Social Work, Michigan Medicine AYA Oncology Program, Ann Arbor, Michigan, USA.ORCID 0000-0002-3199-1113
Meiyan ChenThe University of Texas at Austin School of Social Work, Austin, Texas, USA.ORCID 0009-0003-1283-5961
Rachel BrandonUniversity of Michigan School of Social Work and Department of Psychology, Ann Arbor, Michigan, USA.
Jennifer Currin-McCullochColorado State University School of Social Work, Fort Collins, Colorado, USA.
Xingzhi LiuMichigan Medicine AYA Oncology Program, Ann Arbor, Michigan, USA.
Brennan CheladynMichigan Medicine AYA Oncology Program, Ann Arbor, Michigan, USA.
Betty FerrellCity of Hope Medical Center, Duarte, California, USA.
Barbara JonesBoston University School of Social Work, Boston, Massachusetts, USA.
Bradley ZebrackUniversity of Michigan School of Social Work, Michigan Medicine AYA Oncology Program, Ann Arbor, Michigan, USA.
Adam S DuVallDepartment of Medicine, Assistant Professor of Medicine and Assistant Professor of Pediatrics, University of Chicago, Chicago, Illinois, USA.ORCID 0000-0002-9163-8792

Funding

Cambia Health Sojourns Scholar Leadership Program
6 · The paper itself

Abstract

backgroundPalliative care is critical to the wellness of cancer patients and survivors, but adolescents and young adults (AYAs) with cancer are confronted with the divide between pediatric and adult palliative care as well as pediatric and adult/medical oncology. Consequently, attention to palliative care for AYAs with cancer has just started, and our understanding of palliative care for AYA oncology remains limited.

aimThis study aims to update our understanding of this salient topic through rigorous research synthesis.

designA systematic review of empirical literature was adopted, and data was innovatively analyzed using meta-thematic analysis. The review was pre-registered on OSF (https://osf.io/zy9cs). Studies were searched across ten electronic databases from inception to August 1, 2024 (i.e., the search date). Eligibility criteria include: (1) study the topic of palliative care; (2) focus on AYA cancer; and (3) report empirical data. Meta-thematic analysis and reflexive thematic analysis informed data analysis methods.

resultsFifty-six primary studies from 2004 to 2024, inclusive of 478 data points, were included in the meta-thematic analysis. Five broad themes were identified: (1) the overall state of AYA palliative care; (2) key characteristics of palliative care for AYAs with cancer; (3) AYA palliative care communication, decision-making, and AYA involvement; (4) prevalent symptoms, care preferences, and priorities in palliative care among AYAs with cancer; and (5) effective interventions.

conclusionsKey insights regarding AYA cancer palliative care have been revealed. Notable areas of improvement regarding the delivery of palliative care to AYAs and future research directions have been identified.

Indexed as

NeoplasmsPalliative CareAdolescentEmpirical ResearchHumansYoung Adultadolescent and young adult cancermeta‐thematic analysispalliative caresystematic review

Identifiers

PMID40660632
PMCPMC12260280

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.