Evidence map›Paper›PMID 40660614›Full record

ArticlePsycho-oncology2025

How to Support Participants in Urogenital and Prostate Clinical Trials: A Qualitative Perspective.

Natasha A Roberts, Ian D Davis, David Wyld, Jeffrey Goh, Maxwell Thompson, Craig Gedye, Haryana M Dhillon

Abstract read
In one paragraph

Article in Psycho-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Natasha A RobertsMetro North Health Service, Brisbane, Australia.
Ian D DavisANZUP Cancer Trials Group, Sydney, Australia.
David WyldMetro North Health Service, Brisbane, Australia.
Jeffrey GohMetro North Health Service, Brisbane, Australia.
Maxwell ThompsonMetro North Health Service, Brisbane, Australia.
Craig GedyeANZUP Cancer Trials Group, Sydney, Australia.
Haryana M DhillonANZUP Cancer Trials Group, Sydney, Australia.ORCID 0000-0003-4039-5169

Funding

Australian and New Zealand Urogenital and Prostate Cancer Trials Group
6 · The paper itself

Abstract

backgroundClinical trials are fundamental to improving cancer treatment and clinical outcomes. Whilst clinical trials offer treatment options to affected individuals, less is known about how to best support those who participate.

aimTo explore the experiences of participants in urogenital and prostate cancer clinical trials to identify opportunities to improve care for this cohort of patients.

methodsThis qualitative study was conducted in Australian hospitals. Participants were included if they had consented to participate in an Australian collaborative investigator led clinical trial for prostate or other urogenital cancer. Semi-structured interviews with participants were completed by telephone. Using verbatim transcriptions, their experiences relative to key stages of a clinical trial were analysed using a Framework Method. Findings were interpreted to develop key recommendations for use by investigators developing a clinical trial.

results22 people consented and participated in interviews. They came from rural, regional, and metropolitan areas across Australia. Participants were being treated for advanced uro-genital and prostate cancers. Across interviews, participants spoke about their supportive care needs and how they valued their relationships with the multi-disciplinary research team and the clinical oncology and urology teams. There was variation in participant needs according to the stage of the clinical trial. Despite times of uncertainty, it was reported clinical trial participation was meaningful. Receiving information about overall findings of the clinical trial was important to participants allowing them to understand the impact of their contribution.

conclusionUnderstanding the experiences of clinical trial participants can improve the design of trial protocol processes and procedures. Participants want to stay connected with their clinical trial.

Indexed as

Clinical Trials as TopicProstatic NeoplasmsSocial SupportUrogenital NeoplasmsAdultAgedAustraliaFemaleHumansInterviews as TopicMaleMiddle AgedQualitative Researchcancerclinical trialshealth servicesoncologypatient experiencequalitative researchsupportive care

Identifiers

PMID40660614
PMCPMC12260335

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.