Evidence map›Paper›PMID 40660580›Full record

ArticleMedicine2025

Ultrasound-guided microwave ablation for primary hyperparathyroidism in an elderly patient with pancytopenia: A case report.

Yun Cai, Yanwei Chen, Shuangshuang Zhao, Zheng Zhang, Huajiao Zhao, Feng Zhao, Baoding Chen

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In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Yun CaiDepartment of Ultrasound Medicine, Affiliated Hospital of Jiangsu University, Zhenjiang City, Jiangsu Province, China.
Yanwei Chen
Shuangshuang Zhao
Zheng Zhang
Huajiao Zhao
Feng Zhao

Funding

he Sixth Phase “169 Project†Scientific Research Project of Zhenjiang City YLJ202104the Medical Education Collaborative Innovation Fund of Jiangsu University JDY2023012the National Science Foundation for Young Scientists of China 82302208the Social Development Program of Zhenjiang City SH2022066the Social Development Program of Zhenjiang City SH2023015the Social Development Program of Zhenjiang City SH2023019
6 · The paper itself

Abstract

rationalePrimary hyperparathyroidism (PHPT) is the third major endocrine disorder characterized by increased secretion of parathyroid hormone, with an incidence of up to 3% in elderly women. Although current guidelines consider parathyroidectomy to be the only definitive treatment, it is extremely risky for elderly women with numerous underlying conditions. However, hypercalcemia and other clinical symptoms caused by PHPT can seriously threaten the health and quality of life of patients. Therefore, it is very important to find a safe and effective minimally invasive alternative therapy. Hence, we report a case of ultrasound-guided microwave ablation (MWA) for PHPT in an elderly patient with pancytopenia. PATIENT CONCERNS: A 75-year-old female patient with pancytopenia was diagnosed with PHPT and was admitted for treatment due to her strong desire for treatment. DIAGNOSES: Imaging examination, laboratory examination and ultrasound-guided fine-needle aspiration cytology all led to a diagnosis of PHPT for the patient.

interventionsConsidering the advanced age of the patient, suffering from pancytopenia and other underlying disease, the surgical risk is high, so MWA was selected for this hospitalization. OUTCOMES: We found that after 6 months of treatment, the following 4 indicators of the patient returned to normal (parathyroid hormone, 66.9 pg/mL; ionic calcium, 1.19 mmol/L; serum total calcium, 2.28 mmol/L; phosphorus, 0.80 mmol/L). The lesion volume of the patient gradually decreased, and the reduction rate of lesion volume reached 70.3% by 6 months after ablation. There were no complications, and no parathyroid nodules regenerated during follow-up. LESSONS: Ultrasound-guided MWA represents a safe and effective therapeutic option for elderly patients with PHPT.

Indexed as

Ablation TechniquesHyperparathyroidism, PrimaryMicrowavesPancytopeniaUltrasonography, InterventionalAgedFemaleHumanscontrastelderly patientsenhanced ultrasoundmicrowave ablationprimary hyperparathyroidism

Identifiers

PMID40660580
PMCPMC12263061

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