Evidence map›Paper›PMID 40660411›Full record

ArticleHuman genomics2025

BioSTEM: A modern educational tool for research and innovation in the field of molecular biology and personalized medicine.

George P Patrinos, Stavroula Siamoglou, Konstantinos Lazaros, Vasilios Xirafas, Aristidis G Vrahatis, Christina Mitropoulou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George P PatrinosSchool of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, University of Patras, Patras, Greece. gpatrinos@upatras.gr.
Stavroula SiamoglouSchool of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, University of Patras, Patras, Greece.
Konstantinos LazarosDepartment of Informatics, Ionian University, Corfu, Greece.
Vasilios XirafasSchool of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, University of Patras, Patras, Greece.
Aristidis G VrahatisDepartment of Informatics, Ionian University, Corfu, Greece.
Christina MitropoulouThe Golden Helix Foundation, London, UK.

Funding

European Commission 668353HFRI 2182
6 · The paper itself

Abstract

Personalized Medicine has the potential to transform modern healthcare by tailoring medical decisions to an individual's unique genomic profile. However, its integration into routine clinical practice is hindered by limited genomics education among healthcare professionals and a general lack of public awareness. To address these challenges, we introduce the BioSTEM initiative, an innovative educational tool designed for primary, elementary, and high school students. BioSTEM combines optimized online learning modules with interactive audiovisual content, fostering direct communication between students and educators. It also integrates alternative learning strategies, such as online games and comics, to enhance engagement with topics in Biology, Molecular Biology, Genetics, and Personalized Medicine. Since 2016, BioSTEM has reached over 6,000 students across three countries through a combination of theoretical instruction and hands-on experiments using a portable molecular biology laboratory. Our results indicate that participation in BioSTEM significantly improved students' and educators' perception of their understanding of concepts in Genetics and Personalized Medicine. Participants reported a stronger grasp of genomic concepts and expressed support for incorporating BioSTEM into the standard biology curriculum. These findings suggest that BioSTEM is a promising and scalable approach to advancing biomedical education and fostering the development of genomic-literate citizens.

Indexed as

Molecular BiologyPrecision MedicineAdolescentCurriculumGenomicsHumansStudentsBioSTEMEducational and research toolEducatorsGeneticsHigh schoolMolecular biologyPersonalized medicineScience communicationSTEMStudents

Identifiers

PMID40660411
PMCPMC12261724

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.