Evidence map›Paper›PMID 40660265›Full record

ArticleHarm reduction journal2025

Community-Originated Research to Identify Access Gaps in Over-the-Counter Naloxone Availability in Connecticut Pharmacies.

Katherine Hill, Peter Canning, Zoey Canning, Cameron Breen, Liz Evans, Mark Jenkins, Mark Nickel, Ken Plourd, Robert Heimer

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katherine Hill *Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA.
Peter Canning *Emergency Medical Services, University of Connecticut John Dempsey Hospital, Farmington, CT, USA.
Zoey CanningNorthwest Catholic High School, West Hartford, Connecticut, USA.
Cameron BreenLiberation Programs, Bridgeport, CT, USA.
Liz EvansLiberation Programs, Bridgeport, CT, USA.
Mark JenkinsCT Harm Reduction Alliance, Hartford, CT, USA.
Mark NickelCross Sector Consulting, LLP, Hamden, CT, USA.
Ken PlourdCross Sector Consulting, LLP, Hamden, CT, USA.
Robert HeimerDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, CT, USA. k.hill@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNaloxone, a life-saving medication that reverses opioid overdoses, was available in the United States only by prescription until March 2023, when the federal government approved nasal-spray formulations for over the counter sales to expand access. We assessed the availability of naloxone in a sample of pharmacies across the state of Connecticut.

methodsBetween September 15 and November 24, 2024, trained community-based volunteers surveyed a convenience sample of pharmacies throughout the state, focusing on naloxone signage, availability, cost, and in-store location. Pharmacies were categorized into three groups: chain pharmacies, pharmacies within grocery stores, and independent pharmacies. Summary statistics for the full sample and the three subgroups were tabulated, and differences between groups were analyzed using Fisher's exact tests.

resultsA total of 162 pharmacies across all Connecticut counties were evaluated. While naloxone was available in most pharmacies, it was predominantly kept behind the pharmacy counter (n = 111, 73.5%) or the general checkout counter (n = 46, 30.5%). Fewer than 20% of pharmacies (n = 29) had naloxone easily accessible on an aisle shelf. Pricing was often high (≥ $60), particularly in independent pharmacies (n = 7, 22.6%; p < 0.001). Additionally, fewer than 20% of pharmacies (n = 31) displayed signage related to naloxone availability, and all signage was exclusively in English.

conclusionsDespite widespread availability, naloxone access was restricted by its in-store location, high cost, and inadequate signage. This highlights a notable discrepancy between naloxone availability and accessibility, suggesting a lag in the effective implementation of policy in intended settings.

Indexed as

Health Services AccessibilityNaloxoneNarcotic AntagonistsNonprescription DrugsPharmaciesConnecticutHumansNaloxoneNarcotic AntagonistsNonprescription DrugsNaloxoneNarcanPharmacy

Identifiers

PMID40660265
PMCPMC12261670

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.