ReviewRadiation oncology (London, England)2025
Research trends of selective internal radiation therapy for liver cancer: a bibliometric analysis.
Review in Radiation oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Evolving trends in yttrium-90 radioembolization research: a comprehensive bibliometric study.Annals of nuclear medicine · 2026Article
- Research trends and hot topics of radiation-induced pulmonary fibrosis: a bibliometric analysis and visualization study from 2015 to 2025.Journal of thoracic disease · 2026Article
- Knowledge mapping of ⁹⁰Y transarterial radioembolization combined with immunotherapy in hepatocellular carcinoma: a bibliometric analysis.Discover oncology · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundLiver cancer is a major contributor to cancer-related mortality. Selective internal radiation therapy (SIRT) for liver cancer has garnered increasing attention. This study aims to comprehensively describe the current status, hotspots and trends of SIRT.
methodsPublications from January 1, 1994, to May 31, 2024, were retrieved from the Web of Science Core Collection. CiteSpace, VOSviewer, the Bibliometrix package from R software, and an online analytical platform were used for knowledge mapping analysis and visualization.
resultsA total of 2046 publications were retrieved from the Web of Science Core Collection. The number of publications related to SIRT for liver cancer has been continuously increasing, particularly since 2005. The United States led in publications, and a strong collaboration network was observed among countries, particularly within Europe and America. The Northwestern University had the highest number of publications in the field of SIRT. Co-citation analysis identified "predictive dosimetry" and "atezolizumab" as current focal points within the field. High-frequency keywords include "transarterial radioembolization", "Y90 microspheres", "hepatocellular carcinoma", while recent citation bursts are predominantly centered on "lung shunt fraction," "tumor dose," "systemic therapy," "radiation segmentectomy," "Holmium-166," etc.
conclusionAs a local treatment, SIRT exhibits significant promise for its future role in the management of hepatic malignancies. Numerous studies on SIRT are actively in progress. Our study suggests that radiation segmentectomy may emerge as an important treatment in the future. Moreover, personalized dosimetry, the combination of SIRT with immunotherapy, and the development of novel radioactive agents are identified as pivotal areas for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.