Observational studyBMC endocrine disorders2025
Relationship between level of serum VIT D and insulin resistance in patients with MAFLD.
Observational study in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- [Liver-bone axis: novel mechanisms and strategies for MAFLD regulation].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026Review
- Quantifying the metabolic-inflammatory axis: synergistic value of TyG index and FAI in assessing CAD risk among MAFLD patients.Frontiers in endocrinology · 2026Article
- The interplay between childhood obesity and vitamin D deficiency: mechanisms and implications.Frontiers in pediatrics · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-alcoholic fatty liver disease has been recognized as the most common metabolic liver disease in Western countries, and its prevalence is increasing all over the world. Metabolic syndrome and diabetes mellitus (DM) are closely linked to non-alcoholic fatty liver disease. Because of the close relationship between fatty liver and metabolic illnesses, NAFLD has lately been renamed as Metabolic Associated Fatty Liver Disease. HOMA-IR is thought to be the best indicator of the progression of fatty liver to advanced cirrhosis and fibrosis.
aimto assess the relation between level of serum VIT D and insulin resistance in patients with MAFLD. PATIENTS &
methodsThis cross sectional observational study included 120 subjects (60 control & 60 MAFLD patients), where clinical examination including anthropometric measurements, laboratory tests (CBC, liver and renal function, metabolic profile, serum VIT D, HOMA-IR), ultrasonography and shear wave elastography were performed on all the subjects.
resultsIn MAFLD patients, serum vitamin D levels were statistically significant lower (55%) than in the non-MAFLD group (15%), and they also significantly decreased as steatosis and fibrosis grades increased (P < 0.001). In addition, there is an inverse correlation between serum vitamin D levels and IR in MAFLD patients, but it is not statistically significant.
conclusionVitamin D supplementation may be helpful in the treatment of MAFLD since people with the condition have lower serum vitamin D levels than those without it, and these levels drastically decreased with increasing grades of fatty liver.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.