Evidence map›Paper›PMID 40660201›Full record

ArticleBMC public health2025

Association between Adverse Childhood Events (ACEs) and long-term COVID-19 symptoms: evidence from the 2022 behavioral risk factor surveillance system.

Safa Elkefi, Alana Steffen, Alicia K Matthews

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Safa ElkefiSchool of Nursing, Columbia University, New York, USA. safaelkefi.research@gmail.com.
Alana SteffenSchool of Nursing, University of Illinois Chicago, Chicago, USA.
Alicia K MatthewsSchool of Nursing, Columbia University, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigated the association between Adverse Childhood Events (ACEs) and long-term COVID-19 symptoms.

methodsWe used data from the 2022 Behavioral Risk Factor Surveillance System. Multivariable logistic regression was used to assess the association between long-term COVID symptoms and ACEs, adjusting for demographic characteristics (race/ethnicity, age, and sex). Survey weights were applied.

resultsOf the 14,560 participants, 46.73% experienced 1-3 ACEs, and 26.81% experienced 4 + ACEs-23.38% experienced long-term COVID-19 symptoms. Blacks (OR = 0.76, P =.002) and Asians (OR = 0.56, P =.009) were less likely than Whites to experience long-term COVID-19, but American Indians (OR = 1.72) were more likely. Adults aged 35-69 had a higher likelihood of long-term symptoms than younger adults (OR = 1.24), whereas those aged 70 or older did not differ from younger adults. Females were also more likely to experience them (OR = 1.61). Exposure to ACEs was positively associated with long-term COVID-19 symptoms. The more adverse events individuals were exposed to, the more risk of long-term COVID-19. Specifically, experience of household substance abuse (OR = 1.14, 95%, P =.008), physical abuse (OR = 1.18, 95%, P =.001), emotional abuse (OR = 1.13, 95%, P =.014), sexual abuse (OR = 1.43, 95%, P <.001), and household mental illness (OR = 1.35, 95%, P <.001) were positively associated with the long-term COVID-19 experience.

conclusionsStudy findings contribute to the extensive literature demonstrating the negative health consequences of childhood adversities. More adverse events resulted in more risk to experience long term COVID-19 symptoms. Additional research is needed to better understand and intervene in the biological vulnerabilities associated with childhood adversities.

Indexed as

Adverse Childhood ExperiencesCOVID-19AdolescentAdultAgedBehavioral Risk Factor Surveillance SystemChildFemaleHumansMaleMiddle AgedRisk FactorsUnited StatesYoung AdultAdverse childhood experiencesChildhood maltreatmentHealth effectsTraumaViolence prevention

Identifiers

PMID40660201
PMCPMC12257769

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.