Evidence map›Paper›PMID 40660070›Full record

ReviewThe AAPS journal2025

Prospects and Challenges of Catechins in Cardiovascular Disease.

Yiyang Chen, Yeqing Ren, Kaixin Zhou, Wangrui Lei, Yang Yang, Xue Wang

Abstract readReview
PubMed Publisher
In one paragraph

Review in The AAPS journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yiyang Chen *Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Northwest University First Hospital, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.ORCID 0009-0000-3162-4500
Yeqing Ren *Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Northwest University First Hospital, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.ORCID 0009-0002-7158-3568
Kaixin Zhou *Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Northwest University First Hospital, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.ORCID 0009-0003-7198-3083
Wangrui LeiXi'an Key Laboratory of Innovative Drug Research for Heart Failure, Northwest University First Hospital, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China.ORCID 0009-0005-7255-4082
Yang YangXi'an Key Laboratory of Innovative Drug Research for Heart Failure, Northwest University First Hospital, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China. yang200214yy@nwu.edu.cn.ORCID 0000-0002-1163-2359
Xue WangDepartment of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China. xuewangjiaotong@163.com.ORCID 0009-0000-5701-361X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) have become one of the leading threats to human health due to their high incidence and mortality rates. Their pathological mechanisms are complex, involving inflammation, oxidative stress, energy metabolism, and other factors. Catechins are a group of flavanol derivatives originally extracted from the traditional Chinese medicine Acacia catechu (L.f.) Willd. Their unique polyhydroxy chemical structure endows catechins with a range of biological activities, such as anti-inflammatory properties, antioxidant properties, and the regulation of nutrient homeostasis. Recent studies have shown the beneficial effects of catechins in atherosclerosis, hypertension, heart failure, cardiomyopathy, and other cardiovascular conditions. Therefore, catechins present significant potential as a therapeutic approach for CVDs. This review provides an overview of the structure, pharmacological mechanisms, and recent research developments of catechins in cardiovascular diseases, with the goal of offering insights for the future medicinal study of catechins.

Indexed as

Cardiovascular DiseasesCatechinAnimalsAnti-Inflammatory AgentsAntioxidantsHumansOxidative StressAnti-Inflammatory AgentsAntioxidantsCatechinantioxidantcardiovascular diseasecatechinssignaling pathwaystructure

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.