Trial reportAnnals of biomedical engineering2025
Differential and Adjustable Stiffness Leaf Spring Ankle Foot Orthoses Enhance Gait Propulsion and Task Versatility in Cerebral Palsy.
Trial report in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The trial behind it
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Who cites it
3 citing papers in PubMed.
- Exploratory Assessment of Robotic Ankle Foot Orthosis Stiffness and Neutral Angle on Stair Ambulation in Individuals with Cerebral Palsy.Annals of biomedical engineering · 2026Article
- An integrated multi-variable optimization approach to tailor ankle-foot orthosis stiffness to end-user needs.Journal of neuroengineering and rehabilitation · 2026Article
- Feasibility and Preliminary Response of a Novel Training Program on Mobility Parameters in Adolescents with Movement Disorders.Healthcare (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
purposeThis study explored the effectiveness of a novel differential and adjustable stiffness leaf spring AFO (DAS-AFO) during standing, walking, and sit-to-stand tasks among individuals with cerebral palsy.
methodsEleven individuals with cerebral palsy, ages 12-41, completed treadmill walking trials with the DAS-AFO, a solid (i.e., rigid) AFO, and without an assistive device (shod). We quantified metabolic cost, muscle activity of the soleus and vastus lateralis, and lower body kinetics and kinematics. Participants also performed overground walking, sit-to-stand, and stable standing tasks while wearing the DAS-AFO and reported their preferred stiffness setting for each task. Additionally, we quantified center of pressure during the stable standing task.
resultsWalking with the DAS-AFO resulted in an average 24% increase in ankle push-off power when compared to the solid AFO (p = .003). Both AFO conditions resulted in an average 16% reduction in soleus activity compared to shod (p < .040); only the DAS-AFO reduced vastus lateralis activity compared to shod (13% average reduction, p = .015). Over half of the participants preferred a different AFO stiffness for at least one of the tasks of daily living. No stiffness setting was universally preferred for a single task. During the stable standing task, the high stiffness setting increased average anterior-posterior center of pressure excursion (p = .022) and velocity (p = .001) compared to shod.
conclusionOur findings highlight potential benefits of the DAS-AFO design over solid AFOs, including improved ankle joint motions and push-off power during walking. Customizability of the DAS-AFO positively influenced participant preference and task performance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.