Evidence map›Paper›PMID 40659983›Full record

Trial reportAnnals of biomedical engineering2025

Differential and Adjustable Stiffness Leaf Spring Ankle Foot Orthoses Enhance Gait Propulsion and Task Versatility in Cerebral Palsy.

Collin D Bowersock, Emmanuella A Tagoe, Samuel Hopkins, Shanpu Fang, Zachary F Lerner

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Collin D BowersockOklahoma State University, Human Performance and Nutrition Research Institute, Stillwater, OK, USA. collin.bowersock@okstate.edu.ORCID http://orcid.org/0000-0002-5545-8532
Emmanuella A TagoeNorthern Arizona University, Mechanical Engineering, Flagstaff, AZ, USA.ORCID http://orcid.org/0009-0006-6623-600X
Samuel HopkinsNorthern Arizona University, Mechanical Engineering, Flagstaff, AZ, USA.ORCID http://orcid.org/0009-0005-6033-7304
Shanpu FangNorthern Arizona University, Mechanical Engineering, Flagstaff, AZ, USA.ORCID http://orcid.org/0000-0002-3019-2977
Zachary F LernerNorthern Arizona University, Mechanical Engineering, Flagstaff, AZ, USA. Zachary.Lerner@nau.edu.ORCID http://orcid.org/0000-0002-7359-436X

Funding

An adjustable stiffness orthosis to maintain muscle engagement and push-off power in cerebral palsy.R41HD113494 · NICHD · BIOMOTUM, LLC · PI LERNER, ZACHARY FOREST · 2023 to 2023
$274k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R41HD113494NICHD NIH HHS R41 HD113494
6 · The paper itself

Abstract

purposeThis study explored the effectiveness of a novel differential and adjustable stiffness leaf spring AFO (DAS-AFO) during standing, walking, and sit-to-stand tasks among individuals with cerebral palsy.

methodsEleven individuals with cerebral palsy, ages 12-41, completed treadmill walking trials with the DAS-AFO, a solid (i.e., rigid) AFO, and without an assistive device (shod). We quantified metabolic cost, muscle activity of the soleus and vastus lateralis, and lower body kinetics and kinematics. Participants also performed overground walking, sit-to-stand, and stable standing tasks while wearing the DAS-AFO and reported their preferred stiffness setting for each task. Additionally, we quantified center of pressure during the stable standing task.

resultsWalking with the DAS-AFO resulted in an average 24% increase in ankle push-off power when compared to the solid AFO (p = .003). Both AFO conditions resulted in an average 16% reduction in soleus activity compared to shod (p < .040); only the DAS-AFO reduced vastus lateralis activity compared to shod (13% average reduction, p = .015). Over half of the participants preferred a different AFO stiffness for at least one of the tasks of daily living. No stiffness setting was universally preferred for a single task. During the stable standing task, the high stiffness setting increased average anterior-posterior center of pressure excursion (p = .022) and velocity (p = .001) compared to shod.

conclusionOur findings highlight potential benefits of the DAS-AFO design over solid AFOs, including improved ankle joint motions and push-off power during walking. Customizability of the DAS-AFO positively influenced participant preference and task performance.

Indexed as

AnkleCerebral PalsyFoot OrthosesGaitAdolescentAdultBiomechanical PhenomenaChildFemaleHumansMaleMuscle, SkeletalWalkingYoung AdultAssistive devicesBiomechanicsCenter of pressureLocomotionMotor disability

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.