Evidence map›Paper›PMID 40659950›Full record

ArticleSurgical endoscopy2025

Restoration of normal anatomy without fundoplication in non-elective incarcerated giant paraesophageal hernia repair.

Evan T Alicuben, James D Luketich, Ryan M Levy, Corey Kelsom, Gabriella Lloyd, Tadeusz Witek, Inderpal S Sarkaria, Nicholas Baker, Neil Christie, Omar Awais

Abstract read
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Evan T AlicubenDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA. alicubenet@upmc.edu.ORCID http://orcid.org/0000-0002-5767-9435
James D LuketichDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Ryan M LevyDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Corey KelsomDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Gabriella LloydDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Tadeusz WitekDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Inderpal S SarkariaDepartment of Cardiovascular and Thoracic Surgery, UT Southwestern Medical Center, Dallas, TX, USA.
Nicholas BakerDepartment of Cardiovascular and Thoracic Surgery, WVU Heart and Vascular Institute, Morgantown, WV, USA.
Neil ChristieDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.
Omar AwaisDepartment of Cardiothoracic Surgery, University of Pittsburgh, 5200 Centre Avenue, Suite 715, Pittsburgh, PA, 15232, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe purpose of our study was to examine outcomes following a novel approach to management of incarcerated giant paraesophageal hernia in a non-elective setting. Surgical dogma has dictated performing a fundoplication, but we have hypothesized that this is unnecessary in patients without significant reflux presenting with predominantly obstructive symptoms.

methodsPatients who presented to the emergency room between January 2010 and June 2024 with symptomatic giant incarcerated paraesophageal hernia with operative repair performed during the same hospitalization were included. An absence of pre-operative reflux symptoms was required. Operative steps included hernia sac reduction, mediastinal mobilization with vagal and crural lining preservation and primary crural closure. An Angle of His reconstruction was performed, and the fundus was sutured to the left hemidiaphragm immediately anterior to the spleen. Objective follow-up was obtained via esophagram, endoscopy, and CT scan.

resultsThere were 255 patients with a median age of 81 years. All operations were performed with minimally invasive techniques. The median post-operative length of stay was 6 days. The 30-day mortality was 3.5%, mostly related to complications of pneumonia. Objective follow-up was available in 230 patients at a median of 13 months. There were 13 hiatal hernia recurrences (5.7%): 7 medium (3-4 cm), and 6 large. There were 7 patients that had any heartburn at last follow-up and all were well controlled with medication. Reoperation was performed in 2 patients due to recurrent obstructive symptoms following vomiting episodes. No patient required reoperation for severe reflux.

conclusionMeticulous hiatal hernia repair with crural closure and restoration of normal anatomy is a safe and effective option in patients presenting in non-elective settings without a significant reflux history. Given increased morbidity with urgent operations, elective repair of giant paraesophageal hernia should be considered in all patients.

Indexed as

Hernia, HiatalHerniorrhaphyAgedAged, 80 and overFemaleFollow-Up StudiesFundoplicationHumansLength of StayMaleMiddle AgedPostoperative ComplicationsRecurrenceRetrospective StudiesTreatment OutcomeHiatal herniaParaesophageal herniaUrgent surgery

Identifiers

PMID40659950
PMCPMC12408763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.