ArticleSurgical endoscopy2025
Risk factors associated with failure to rescue after minimally invasive Ivor Lewis esophagectomy.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- A new paradigm for esophageal disease management: the application and future prospects of Shared Decision Making (SDM).World journal of surgical oncology · 2026Review
- How to Promote Minimally Invasive Esophagectomy Safely and Contribute to Improved Prognosis of Esophageal Cancer Patients in the Neoadjuvant Treatment Era?World journal of surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the clinical factors associated with failure to rescue (FTR) among patients who underwent minimally invasive Ivor Lewis esophagectomy (MIE).
methodsRetrospective analysis of all adults (≥ 18 years) who underwent a MIE from September 2013 to September 2023. FTR was defined as mortality rate among patients who developed any postoperative complication (any Clavien-Dindo grade). Univariable logistic regression was used to determine which factors were associated with FTR and those significant at p < 0.05 were entered into a multivariable model. Additionally, a stratified analysis was performed to explore the factors associated with FTR among those patients who developed life-threatening complications (Clavien-Dindo 4).
resultsA total of 282 consecutive patients underwent MIEs during the study period. Of these, 138 (49%) developed at least one complication and 11 (4%) were classified as FTR. On univariable analysis, patients > 75 years of age or with cardiac comorbidities were 4 times more likely (OR 3.98, 95% CI 1.11-14.20, p = 0.033) and 4.7 times more likely (OR 4.70, 95% CI 1.19-18.58, p = 0.028) to experience FTR, respectively. Multivariable analysis revealed that age ≥ 75 years (OR 2.86, 95% CI 0.76-10.75, p = 0.120) and cardiac comorbidities (OR 3.75, 95% CI 0.91-15.50, p = 0.061) were associated with increased odds of FTR. Additionally, stratified univariable analysis among patients who developed life-threatening complications (Clavien-Dindo 4) showed no association with FTR.
conclusionsAge and cardiac comorbidities are risk factors associated with FTR in patients undergoing MIE. These findings highlight the importance of preoperative risk stratification and optimization, as well as patient-provider shared decision-making, to reduce perioperative morbidity and mortality. Further studies are needed to develop perioperative strategies to reduce the rates of failure to rescue and improve the overall survival of this population.
Indexed as
Identifiers
40659946What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.