Evidence map›Paper›PMID 40659909›Full record

ArticlePediatric research2026

Genetic regulation of body size and morphology from adolescence to early adulthood.

Karri Silventoinen, Robert F Krueger, Aline Jelenkovic, Reijo Sund, Glenn I Roisman, Jaakko Kaprio, Matt McGue

Abstract readTwin Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Karri SilventoinenHelsinki Institute for Demography and Population Health, University of Helsinki, Helsinki, Finland. karri.silventoinen@helsinki.fi.
Robert F KruegerDepartment of Psychology, University of Minnesota Twin Cities, Minneapolis, MI, USA.
Aline JelenkovicDepartment of Genetics, Physical Anthropology and Animal Physiology, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Bilbao, Spain.
Reijo SundInstitute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Glenn I RoismanInstitute of Child Development, University of Minnesota Twin Cities, Minneapolis, MI, USA.
Jaakko KaprioInstitute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland.
Matt McGueDepartment of Psychology, University of Minnesota Twin Cities, Minneapolis, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe analyzed the shared genetic background of extensive anthropometric measurements, determining body size and morphology.

methodsAnthropometric measurements were taken for 15 traits from 1512 US twins at an average age of 11.7 years (Minnesota, 51% females) and for 20 traits at an average age of 14.8 years for males (N = 624) and 18.1 years for females (N = 505). Genetic twin modeling was utilized to estimate the genetic correlations between these traits.

resultsIn mid to late adolescence, high genetic correlations were found within height-related traits and foot length (r

conclusionsShared genetic variation plays a significant role in human body size and morphology as well as their development during adolescence. IMPACT: There are clusters of anthropometric traits showing high genetic correlations. The highest genetic correlations were found within height- and adiposity-related traits. Nearly all anthropometric traits share some genetic variation. Genetic factors importantly contribute to the growth of all traits during adolescence. Pleiotropic effects are important for understanding the genetic regulation of human physique.

Indexed as

Body SizeAdiposityAdolescentAnthropometryBody HeightChildFemaleHumansMaleModels, GeneticPhenotypeYoung Adult

Identifiers

PMID40659909
PMCPMC13021503

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