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ArticleClinical neuroradiology2025

3D T1-Weighted Black-Blood MRI in the Diagnosis and Follow-Up of Facial Neuritis: a Single-Center Prospective Study.

Ahmet Kursat Karaman, Bora Korkmazer, Ahmet Öz, Nursena Erener, Musa Musayev, Cesur Samancı, Melih Tütüncü, Alperen Vural, Yetkin Zeki Yılmaz, Osman Kızılkılıç and 1 more

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Article in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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11 authors.

Ahmet Kursat KaramanDepartment of Radiology, Sureyyapasa Chest Diseases and Thoracic Surgery Training Hospital, Istanbul, Turkey.
Bora KorkmazerDivision of Neuroradiology, Department of Radiology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Ahmet ÖzDepartment of Radiology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Nursena ErenerDepartment of Neurology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Musa MusayevDepartment of Otorhinolaryngology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Cesur SamancıDepartment of Radiology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Melih TütüncüDepartment of Neurology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Alperen VuralDepartment of Otorhinolaryngology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Yetkin Zeki YılmazDepartment of Otorhinolaryngology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Osman KızılkılıçDivision of Neuroradiology, Department of Radiology, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Serdar ArslanDivision of Neuroradiology, Department of Radiology, Istanbul University-Cerrahpasa, Istanbul, Turkey. serdararslan@iuc.edu.tr.ORCID http://orcid.org/0000-0001-7984-4326

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the diagnostic performance of 3D T1-weighted black-blood (T1W BB) MRI compared to 3D T1-weighted turbo field echo (T1-TFE) in diagnosing facial neuritis (FN) and to investigate its role in disease monitoring. MATERIALS AND

methods22 patients with acute idiopathic FN were included in this prospective study. All patients underwent MRI within the first week of clinical presentation including 3D T1W BB and 3D T1-TFE sequences. Two neuroradiologists independently analyzed six facial nerve segments, evaluating contrast enhancement using a three-point grading scale (0-2). Diagnostic accuracy, sensitivity, specificity, and area under the curve (AUC) were compared between the two sequences. Follow-up MRI was performed in 8 patients to monitor temporal changes in nerve enhancement, and these findings were analyzed in relation to House-Brackmann (HB) scores.

resultsThe sensitivity, specificity, and accuracy for FN detection were 97.7%, 93.2%, and 95.5% for 3D T1W BB, compared to 86.4%, 97.7%, and 92% for 3D T1-TFE, respectively. Sensitivity was significantly higher with 3D T1W BB (p < 0.05), while AUCs were higher but not significant for both readers. Mean enhancement grades in all affected nerve segments were significantly higher on 3D T1W BB (p < 0.05). Follow-up imaging showed enhancement reduction in 87.5% of patients, correlating with HB score improvements. Enhancement grades significantly correlated with HB scores on T1W BB but not on T1-TFE.

conclusion3D T1W BB has comparable diagnostic performance with 3D T1-TFE for diagnosing FN and can be used as an effective tool in confirming the diagnosis and in follow-up.

Indexed as

Facial Nerve DiseasesImaging, Three-DimensionalMagnetic Resonance ImagingAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesSensitivity and SpecificityYoung AdultBell’s palsyBlack-blood imagingFacial neuritisMagnetic resonance imaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.