ArticleMolecular psychiatry2025
A medial habenula neural circuit controlling anxiety-like behaviors in response to acute stress.
Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Differential effects of acute, chronic, and social defeat stress on microglial morphology in the basolateral and central amygdala, and the medial and lateral habenula.Brain structure & function · 2026Article
- Substance P in the lateral hypothalamic area regulates binge-like eating behaviors in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Nicotinic Receptors in the Medial Habenula to Interpeduncular Nucleus Pathway: Modulators of Reward, Aversion and Emotion.The European journal of neuroscience · 2025Review
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Authors and funding
11 authors.
Funding
Abstract
Anxiety is characterized by worried thoughts and an aversion to immediate threats. While the neural circuits underlying anxiety have been studied, the underlying circuit mechanisms remain largely unknown. Here, we report that the activity of tachykinin-expressing (Tac1) neurons in the medial habenula (MHb) is decreased and excitatory projections from these neurons are inhibited in response to acute stress in mice. Activation of interfascicular nucleus (IF)
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.