Evidence map›Paper›PMID 40659670›Full record

ArticleScientific data2025

A comprehensive dataset of therapeutic peptides on multi-function property and structure information.

Baichuan Xiao, Yixiang Zhou, Long Zhao, Haodong Huang, Xuwen Fei, Yong-Biao Zhang

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. A deep reinforcement learning platform for antibiotic discovery.bioRxiv : the preprint server for biology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Baichuan Xiao *School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Yixiang Zhou *School of Engineering Medicine, Beihang University, Beijing, 100191, China.
Long Zhao *School of Materials and Chemical Engineering, Beijing Institute of Petrochemical Technology, Beijing, 102627, China.
Haodong HuangSchool of Engineering Medicine, Beihang University, Beijing, 100191, China.
Xuwen FeiSchool of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China.
Yong-Biao ZhangSchool of Engineering Medicine, Beihang University, Beijing, 100191, China. zhangyongbiao@buaa.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32470644National Natural Science Foundation of China (National Science Foundation of China) 82171844
6 · The paper itself

Abstract

This paper presents a comprehensive dataset comprising 58,583 experimentally validated therapeutic peptides with annotated structure information. These peptides are grouped into 47 categories based on their function or therapeutic property like antimicrobial or glucose-regulatory, of which 21,130 are multi-function peptides and 54,722 possess structural annotation information. We believe this dataset can be useful for the relevant research of therapeutic peptides, especially for computational tool developments in therapeutic peptide discovery and further exploration of the 'sequence-structure-function' relationship for therapeutic peptides.

Indexed as

PeptidesStructure-Activity RelationshipPeptides

Identifiers

PMID40659670
PMCPMC12259882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.