Evidence map›Paper›PMID 40659599›Full record

ArticleESC heart failure2025

Clinical impact of tricuspid regurgitation in patients with acute myocardial infarction.

Shun Nishino, Chiharu Nishino, Michikazu Nakai, Kensaku Nishihira, Nehiro Kuriyama, Yoshisato Shibata

Abstract read
In one paragraph

Article in ESC heart failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shun NishinoDepartment of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.ORCID https://orcid.org/0000-0001-5879-4382
Chiharu NishinoDepartment of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.
Michikazu NakaiClinical Research Support Center, University of Miyazaki Hospital, Miyazaki, Japan.
Kensaku NishihiraDepartment of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.
Nehiro KuriyamaDepartment of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.
Yoshisato ShibataDepartment of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center, Miyazaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe clinical impact of tricuspid regurgitation (TR) in patients after acute myocardial infarction (AMI) is largely unknown. The aim of this study was to clarify the prevalence and prognostic impact of TR in post-AMI patients treated with appropriate primary percutaneous coronary intervention (PCI). METHODS AND

resultsThree hundred fifty-one consecutive patients with first-onset AMI who underwent successful primary PCI from July 2014 to December 2018 were retrospectively examined. Standard two- and three-dimensional echocardiography were performed at discharge. Based on the presence or absence of mild or greater TR, patients were divided into TR (+) and TR (-) groups, respectively. The primary outcome was the incidence of major adverse cardiac events (MACE), defined as the composite of death, re-hospitalization for congestive heart failure and recurrent MI. Seventy-eight (22.2%) patients had mild or greater TR. Kaplan-Meier analysis showed that the cumulative 6-year incidence of MACE was significantly higher in the TR (+) group (hazard ratio, 2.56 [95% confidence interval, 1.48-4.44]; P < 0.001). In the analysis of the severity of TR, the prognosis of patients with mild TR was significantly worse than that of patients without TR (P = 0.026). Multivariable analysis identified the left anterior descending coronary artery as the culprit vessel, left atrial dilation (>34 mL/m

conclusionsThe presence of mild or greater TR at discharge may serve as a poor prognostic marker in patients with first-onset AMI. In addition to traditional clinical risk factors, it is important to pay more attention to TR and to manage it appropriately.

Indexed as

Myocardial InfarctionPercutaneous Coronary InterventionTricuspid Valve InsufficiencyAgedEchocardiography, Three-DimensionalFemaleFollow-Up StudiesHumansIncidenceMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSurvival RateEchocardiographyMyocardial infarctionPrognosisThree‐dimensional echocardiographyTricuspid regurgitationValvular heart disease

Identifiers

PMID40659599
PMCPMC12450824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.