Evidence map›Paper›PMID 40658881›Full record

ArticleCritical care explorations2025

Troubleshooting Severe Airflow Obstruction With a Pressure-Limited Transport Ventilator: Lessons From Two Cases.

Peter M Reardon, Melody J Bishop, Christopher J Yarnell, Jason A Benaim, Chris Barclay, G Veronica Tello, Andy Pan

Abstract readCase Reports
In one paragraph

Article in Critical care explorations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Peter M ReardonDepartment of Critical Care, Scarborough Health Network, Toronto, ON, Canada.ORCID 0000-0003-2118-1229
Melody J BishopClinical Affairs, Ornge Transport Medicine, Mississauga, ON, Canada.
Christopher J YarnellDepartment of Critical Care, Scarborough Health Network, Toronto, ON, Canada.
Jason A BenaimClinical Affairs, Ornge Transport Medicine, Mississauga, ON, Canada.
Chris BarclayClinical Affairs, Ornge Transport Medicine, Mississauga, ON, Canada.
G Veronica TelloClinical Affairs, Ornge Transport Medicine, Mississauga, ON, Canada.
Andy PanClinical Affairs, Ornge Transport Medicine, Mississauga, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presentations of status asthmaticus or severe chronic obstructive pulmonary disease exacerbation can present a formidable challenge to effective invasive ventilation. The optimal ventilation strategy targets low respiratory rates and high inspiratory flow rates to prolong the expiratory time and minimize dynamic hyperinflation. Although the resulting high peak pressures can usually be accommodated by ICU ventilators, some ventilators have a relatively limited peak pressure capacity as determined by the turbine. Here, we describe two cases of severe airflow obstruction where the desired ventilation strategy required a peak pressure over the capacity of the Hamilton T1 transport ventilator. Changing to a pressure regulated strategy, maximizing the driving pressure, and titrating the inspiratory time overcame the limitation. But, this strategy comes at a cost. Clinicians should be made aware of the possibility of a pressure limitation in their ventilator and understand how to adjust their ventilation strategy appropriately during transitions.

Indexed as

Pulmonary Disease, Chronic ObstructiveRespiration, ArtificialStatus AsthmaticusVentilators, MechanicalHumansauto positive end-expiratory pressurechronic obstructive pulmonary diseasepulmonary ventilationstatus asthmaticus

Identifiers

PMID40658881
PMCPMC12440464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.