Evidence map›Paper›PMID 40658847›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Sleeping upside-down: Knockdown of a sleep-associated gene induces daytime sleep in the jellyfish

Michael J Abrams, Aki Ohdera, Diana A Francis, Owen Donayre, Henry Chen, Kevin Lu, Celeste Y Hsu, Hannah Zeigler, Richard M Harland

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Michael J AbramsDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0003-1864-1706
Aki OhderaDepartment of Mathematics, University of Arizona, Tucson, AZ 85721.
Diana A FrancisDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Owen DonayreDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0002-5933-473X
Henry ChenDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0001-7795-9541
Kevin LuDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0009-0000-2190-9780
Celeste Y HsuDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0009-0005-7050-4727
Hannah ZeiglerDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.
Richard M HarlandDepartment of Molecular and Cell Biology, University of California, Berkeley, CA 94720.ORCID 0000-0001-8247-4880

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The conservation of sleep among diverse animals provides clear evidence for its physiological importance, but the extent of its regulatory conservation is unknown. The upside-down jellyfish

Indexed as

Receptors, NicotinicScyphozoaSleepAnimalsGangliaGene Knockdown TechniquesSleep DeprivationWakefulnessReceptors, Nicotinicbehaviorevolutionjellyfishregulationsleep

Identifiers

PMID40658847
PMCPMC12305049

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.