ArticleThe Journal of clinical endocrinology and metabolism2026
Trends of Diabetes in Youth (TrenDY) During COVID-19 Across the United States.
Article in The Journal of clinical endocrinology and metabolism, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Structural Characterisation ofMolecules (Basel, Switzerland) · 2026Article
- Youth-Onset Type 2 Diabetes Before and After COVID-19 Pandemic-Related Public Health Restrictions: Trends in Incidence, Severity, and Remission.Journal of clinical medicine · 2025Article
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Authors and funding
13 authors.
Funding
Abstract
contextThe frequency and acuity at diagnosis of youth-onset type 1 diabetes (T1D) and type 2 diabetes (T2D) were reported as higher in the first year of the COVID-19 pandemic, but it is unclear if these trends persist.
objectiveTo describe trends in new cases of youth-onset diabetes comparing the first 2 years of the COVID-19 pandemic with the 2 preceding years.
designRetrospective study.
settingTwenty-three clinical centers in the United States. PATIENTS: New-onset T1D and T2D in youth between March 1, 2018, and February 28, 2022.
main outcome measuresNew diagnosis of youth-onset T1D or T2D and acuity at diagnosis.
resultsA total of 4851 youth were diagnosed with T1D in the prepandemic period [year (Yr) 1: March 1, 2018, to February 28, 2019; Yr 2: March 1, 2019, to February 29, 2020] and 5955 individuals during the pandemic (Yr 3: March 1, 2020, to February 29, 2021; Yr 4: March 1, 2021, to February 28, 2022), a 22.8% increase (nonsignificant). The proportion of diabetic ketoacidosis in T1D was higher during (43.41%) vs prepandemic (37.77%, P < .01). For T2D, 1610 youth were diagnosed in the prepandemic period while 3443 patients were diagnosed with T2D during the pandemic (a 114% increase). The increase in frequency of T2D attributable to the pandemic from Yr 2 to Yr 3 was 76.8% (P < .01), while the increase from Yr 3 to Yr 4 was not significant.
conclusionIn youth, the frequency of both T1D and T2D increased during the COVID-19 pandemic but was significant only for T2D. When controlled for yearly trends, only the frequency of T2D increased significantly in the first year of the pandemic, suggesting that the pandemic environment differentially impacted rates of T1D and T2D in youth.
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