ArticlePLOS global public health2025
Chorioamnionitis and its associated factors among women admitted to the maternity unit of Public Hospitals in Addis Ababa, Ethiopia.
Article in PLOS global public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Abstract
Chorioamnionitis is a medical illness marked by maternal fever, leukocytosis, tachycardia, uterine discomfort, and preterm membrane rupture. Chorioamnionitis affects approximately 4% of full-term deliveries worldwide, but it is more common in preterm pregnancies and early membrane rupture. This study aimed to assess the prevalence and associated factors of chorioamnionitis among mothers in public hospitals in Addis Ababa, Ethiopia.A hospital-based cross-sectional study was conducted among maternity patients at Zewditu Memorial, Gandhi Memorial, and Abebech Gobena MCH Hospitals from June 15 to July 15, 2024. A simple random sampling technique with proportional size allocation was used to select a total sample of 379 patients. Data were collected using an interviewer-administered questionnaire and analyzed with SPSS version 26.Binary logistic regression was used to analyze the association between dependent and independent variables. Significance was set at p < 0.05 with a 95% confidence interval, and data were presented in tables and graphs.A total number of 356 patient's data were analysed and the proportion of patients with Chorioamnionitis was found to be 21.3%. After adjustment for possible confounders on multi-variable binary logistic regression analysis age < 25 years [AOR = 0.26, 95% CI (0.09-0.72)], having premature rupture of membrane [AOR = 2.24, 95% CI (1.05-4.78)], duration of labor < 12 hour [AOR = 0.10, 95% CI (0.04-0.24)], and having urinary tract infection [AOR = 3.54, 95% CI (1.72-7.27)] were the significant variable associated with Chorioamnionitis. Chorioamnionitis is a common complication in maternity patients. The magnitude of Chorioamnionitis in the selected public hospital was 21.3%. Age, premature rupture of membrane, duration of labor and urinary tract infection were the factors that had significant association with Chorioamnionitis. The Ministry of Health should focus on creating strategies to prevent and intervene in Chorioamnionitis for patients with premature rupture of membranes and prolonged labor.
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