Evidence map›Paper›PMID 40658310›Full record

ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2025

Asian consensus on normothermic intraperitoneal and systemic treatment for gastric cancer with peritoneal metastasis.

Zhenggang Zhu, Joji Kitayama, Hyung-Ho Kim, Jimmy Bok-Yan So, Hui Cao, Lin Chen, Xiangdong Cheng, Jiankun Hu, Motohiro Imano, Hironori Ishigami and 21 more

Abstract readConsensus Statement
In one paragraph

Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Catheter based intraperitoneal chemotherapy using taxane for peritoneal metastases from gastric cancer: from bench to bedside-a narrative review.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Review
  2. Article
  3. Intraperitoneal paclitaxel plus intravenous fluorouracil, leucovorin, oxaliplatin (FOLFOX) and nivolumab for gastric cancer with peritoneal metastasis: results from the IPLUS Phase II study.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Zhenggang Zhu *Department of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China. zzg1954@hotmail.com.ORCID 0009-0007-1795-0706
Joji Kitayama *Department of Gastrointestinal Surgery, Clinical Research Center, Jichi Medical University, Jichi Medical University Hospital, Shimotsuke, Japan.
Hyung-Ho Kim *Department of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Jimmy Bok-Yan So *Department of Surgery, National University Hospital, Singapore, Singapore.
Hui CaoDepartment of General Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lin ChenDepartment of General Surgery, Peking University International Hospital, Beijing, China.
Xiangdong ChengZhejiang Provincial Research Center for Upper Gastrointestinal Tract Cancer, Zhejiang Cancer Hospital, Hangzhou, China.
Jiankun HuDepartment of Gastrointestinal Surgery and Laboratory of Gastric Cancer, West China Hospital, Sichuan University, Chengdu, China.
Motohiro ImanoDepartment of Surgery, Faculty of Medicine, Kindai University, Higashiosaka, Japan.
Hironori IshigamiDepartment of Chemotherapy, The University of Tokyo Hospital, Bunkyo, Japan.
Ye Seob JeeDepartment of Surgery, Dankook University Hospital, Dankook University College of Medicine, Cheonan, Korea.
Jong-Han KimDepartment of Surgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Yasuhiro KoderaDepartment of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Han LiangDepartment of Gastric Cancer, Tianjin Medical University Cancer Institute & Hospital, Tianjin, China.
Xiaowen LiuDepartment of Gastric Cancer Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Sheng LuDepartment of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China.
Yiping MouDepartment of Gastroenterology & Pancreatic Surgery, Zhejiang Provincial People's Hospital, Hangzhou, China.
Mingming NieDepartment of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Won Jun SeoDivision of Foregut Surgery, Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Yanong WangDepartment of Gastric Cancer Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Dan WuDepartment of General Surgery, The Second Affiliated Hospital of Medical College, Hangzhou, China.
Zekuan XuDepartment of General Surgery, Jiangsu Province Hospital, First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hironori YamaguchiDepartment of Surgery, Division of Clinical Oncology, Jichi Medical University, Shimotsuke, Japan.
Chao YanDepartment of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China.
Zhongyin YangDepartment of General Surgery, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China.
Kai YinDepartment of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Yutaka YonemuraPeritoneal Dissemination Center, Kishiwada Tokushukai Hospital, Kishiwada, Japan.
Wei-Peng YongDepartment of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore.
Jiren YuDepartment of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jun ZhangDepartment of Oncology, Shanghai Key Laboratory of Gastric Neoplasms, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai, China.
Asian Gastric Cancer NIPS Treatment Collaborative Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal metastasis (PM) is a major challenge in advanced gastric cancer (GC) with poor prognosis. Normothermic intraperitoneal and systemic treatment (NIPS) has become a promising therapeutic approach. This consensus aims to provide practical recommendations for NIPS treatment for gastric cancer with peritoneal metastasis (GCPM). The GRADE standards were used to rank evidence, and the Delphi method was employed for expert voting. 30 experts from China, Japan, South Korea, and Singapore participated in the development of this consensus. 28 experts participated in the voting process, which produced 29 statements covering diagnostic approaches, patient selection criteria, treatment regimens, management of intraperitoneal port placement, and conversion surgery considerations, and post-surgical treatment strategies in NIPS therapy. Based on current evidence and expert experience, these statements aim to improve the clinical outcomes of NIPS therapy for GCPM patients.

Indexed as

Antineoplastic AgentsChemotherapy, AdjuvantPeritoneal NeoplasmsStomach NeoplasmsAsiaDelphi TechniqueHumansInfusions, ParenteralPatient SelectionTreatment OutcomeAntineoplastic AgentsConsensusConversion surgeryGastric cancerNIPSNormothermic intraperitoneal chemotherapyPeritoneal metastasis

Identifiers

PMID40658310
PMCPMC12378189

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.