Evidence map›Paper›PMID 40658254›Full record

ArticleInternational journal of colorectal disease2025

Association of urinary dysfunction after lower rectal cancer surgery with renal function: a single-center study.

Ryosuke Kikuchi, Kazuhito Sasaki, Yusuke Sato, Aya Niimi, Akira Sakamoto, Hiroaki Nozawa, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Kensuke Kaneko and 2 more

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ryosuke KikuchiDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Kazuhito SasakiDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan. sasakik-tky@umin.ac.jp.
Yusuke SatoDepartment of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Aya NiimiDepartment of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Akira SakamotoDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroaki NozawaDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Koji MuronoDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Shigenobu EmotoDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Yuichiro YokoyamaDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Kensuke KanekoDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Haruki KumeDepartment of Urology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Soichiro IshiharaDepartment of Surgical Oncology, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUrinary dysfunction (UD) is still a major complication after lower rectal cancer (LRC) surgery. Untreated UD is an independent risk factor for renal dysfunction due to repeated urinary reflux and urinary tract infections. However, the relationship between postoperative UD and renal function following LRC surgery remains unclear. In this study, we investigated the impact of UD on renal function post-surgery.

methodsWe retrospectively evaluated 83 patients with LRC who underwent curative resection at our tertiary referral center between April 2015 and December 2018. UD was diagnosed as a post-void residual urine volume ≥ 50 mL using uroflowmetry tests after discharge. We compared the estimated glomerular filtration rate (eGFR) and the incidence of chronic kidney disease (CKD)-defined as an eGFR < 60 mL/min/1.73 m

resultsOf the 83 patients, 21 (25%) had UD. Patients with UD were older, underwent more extensive surgery, and had significantly longer operation times than those without UD. Within 3 years post-surgery, the UD group experienced a higher incidence of urinary tract complications and CKD, with a notable decrease in eGFR. Additionally, a history of hypertension and UD were identified as independent risk factors for CKD at 3 years post-surgery.

conclusionsPatients with UD showed a significant decrease in eGFR and were more likely to progress to CKD at 3 years after LRC surgery. These findings indicated that postoperative UD might adversely affect renal function in patients with LRC.

Indexed as

KidneyPostoperative ComplicationsRectal NeoplasmsAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedRenal Insufficiency, ChronicRetrospective StudiesRisk FactorsLower rectal cancerPostoperative renal dysfunctionPostoperative urinary dysfunctionUrinary tract complicationsUroflowmetry test

Identifiers

PMID40658254
PMCPMC12259756

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