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ArticleInternational urology and nephrology2026

Water vapor thermal therapy for patients with large prostates (≥ 80 mL): initial real-world data from China.

Peishan Wu, Yukun Liu, Dawei Cai, Bo Song, Lingna Zhao, Guangqi Kong

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Article in International urology and nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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6 authors.

Peishan WuDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China.
Yukun LiuDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China.
Dawei CaiDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China.
Bo SongDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China.
Lingna ZhaoDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China.
Guangqi KongDepartment of Urology, Beijing Luhe Hospital, Capital Medical University, No. 82 Xinhua South Road, Tongzhou District, Beijing, 101149, China. summerharvest11@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the safety and efficacy of water vapor thermal therapy (WVTT) in Chinese patients with large prostates (≥ 80 mL).

methodsA retrospective analysis was conducted on patients with large prostates (≥ 80 mL) who underwent WVTT between January 2023 and September 2024. Symptom scores, including the International Prostate Symptom Score (IPSS), Overactive Bladder Symptom Score (OABSS), and IPSS Quality of Life (QoL), along with clinical outcomes, were assessed.

resultsA total of 57 patients (mean age: 73.88 ± 8.71 years; mean prostate volume: 109.27 ± 27.74 mL) were analyzed. Prostatic median lobe was identified in 64.91% (37/57) of patients. The mean surgical time was 29.13 ± 17.36 min, with 12.98 ± 2.19 vapor injections per patient. At 3 months after surgery, 39 patients completed the follow-up. Significant improvements were observed, including a 51.31% reduction in IPSS (p < 0.001) and a 56.50% improvement in IPSS QoL (p < 0.001). Patients with a prostatic median lobe were younger (mean age: 71.97 ± 8.94 vs. 77.40 ± 7.04 years, p = 0.041) and required more vapor injections (13.43 ± 1.95 vs. 12.11 ± 2.36, p = 0.040). No Clavien-Dindo grade III complications occurred, and the surgical re-treatment rate was 5.13% (2/39).

conclusionsWVTT resulted in significant improvements in symptoms and quality of life for Chinese patients with large prostates, with low re-treatment rates and minimal complications at the 3-month follow-up. Larger cohorts and longer follow-up are needed for further evaluation.

Indexed as

ProstateProstatic HyperplasiaSteamAgedAged, 80 and overChinaHumansMaleMiddle AgedOrgan SizeQuality of LifeRetrospective StudiesTreatment OutcomeSteamLarge prostateProstatic median lobeRezūmWater vapor thermal therapy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.