ArticleAbdominal radiology (New York)2026
Safety and diagnostic yield of percutaneous ultrasound-guided penile mass biopsy.
Article in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
objectivesTo evaluate the safety, tolerability, and efficacy of ultrasound-guided percutaneous biopsy of penile masses.
methodsA retrospective review of an institutional biopsy database was used to identify ultrasound-guided percutaneous biopsies of the penis performed between September 2004 and April 2025. Relevant clinical history, pre-biopsy imaging, biopsy technique, sedation plan, complications, final pathology, peri-procedural pain scores, and administered medications were recorded. Safety, tolerability, and efficacy of ultrasound-guided percutaneous biopsy of the penis were assessed.
resultsThere were 15 patients who underwent 16 ultrasound-guided percutaneous penile mass biopsies. Procedures were performed as core-needle biopsies (CNB) using 18- or 20-gauge devices (n = 9), as fine needle aspiration (FNA) using 25-gauge needles (n = 5), or as a combination of 25-gauge FNA and 20-gauge CNB (n = 2). Most biopsies were performed using local anesthetic only (9/16, 56%), or local anesthetic in conjunction with moderate sedation (7/16, 44%). One patient received a dorsal penile nerve block in addition to moderate sedation. The procedures were well-tolerated, with only a single patient reporting periprocedural pain scores above 2. No major complications occurred. A single patient developed a small-to-moderate hematoma which was managed conservatively. Most cases yielded diagnostic tissue (14/16, 87.5%). In the two cases with nondiagnostic tissue, no malignancy was discovered on subsequent workup.
conclusionUltrasound-guided percutaneous biopsy is a safe, well-tolerated, and efficacious procedure that should be considered a viable technique for sampling penile masses.
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