ArticleAnesthesia progress2025
Anesthetic Management With Remimazolam for Adolescent Mitochondrial Encephalomyopathy With Lactic Acidosis and Stroke-like Episodes (MELAS): A Case Report.
Article in Anesthesia progress, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Reply to Commentary: Finsterer, J. Outcome of General Anesthesia With Remimazolam in a m.3243A>G Carrier. Anesthesia Progress. 2026;73(1):51. doi: 10.2344/25-0017.Anesthesia progress · 2026Article
- Outcome of General Anesthesia With Remimazolam in a m.3243A>G Carrier.Anesthesia progress · 2026Article
- Perioperative Care of a Child With Combined Oxidative Phosphorylation Deficiency 6: Total Intravenous Anesthesia With Remimazolam.Journal of medical cases · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We successfully anesthetized a 15-year-old male dental patient with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome using remimazolam and remifentanil. During the rapid sequence induction, we administered intravenous continuous infusions of remimazolam and remfentanil along with boluses of fentanyl and rocuronium to quickly induce general anesthesia without complications. General anesthesia was maintained during the operation with continuous infusions of remimazolam (0.8-1.0 mg/kg/h) and remifentanil (0.15-0.2 μg/kg/min) while using a SedLine monitor to help assess anesthetic depth. Except for immediately after extubation, the patient was stable postoperatively. He progressed satisfactorily and was discharged safely the following day. This experience suggests that the combination of remimazolam and remifentanil is an effective anesthetic for adolescent patients with MELAS syndrome undergoing dental procedures requiring general anesthesia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.