Evidence map›Paper›PMID 40657709›Full record

ArticleJournal of primary care & community health

Opportunistic Use of Chest X-Ray for Identifying Older Adults at risk of Osteoporosis and not Meeting Criteria for Screening.

Naga Ramesh Chinapuvvula, Marsha Hatley, Raia Khan, Muhammad Awiwi, Jude des Bordes, Nahid Rianon

Abstract read
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Article in Journal of primary care & community health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Preventing fragility fractures: AI-based opportunistic osteoporosis detection in routine CT ​.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naga Ramesh ChinapuvvulaDepartment of Diagnostic and Interventional Imaging, University of Texas McGovern Medical School, Houston TX, USA.
Marsha HatleyDepartment of Family and Community Medicine, University of Texas McGovern Medical School, Houston TX, USA.ORCID 0009-0004-7331-5019
Raia KhanJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Texas McGovern Medical School, Houston, TX, USA.
Muhammad AwiwiDepartment of Diagnostic and Interventional Imaging, University of Texas McGovern Medical School, Houston TX, USA.
Jude des BordesJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Texas McGovern Medical School, Houston, TX, USA.ORCID 0000-0002-0747-8117
Nahid RianonJoan and Stanford Alexander Division of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Texas McGovern Medical School, Houston, TX, USA.ORCID 0000-0003-0075-5836

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionScreening for osteoporosis is mainly done by measuring bone mineral density using dual-energy X-ray absorptiometry (DXA) scan. Screening does not usually start until 65 years. Many people 50 to 65 years may unknowingly suffer from progressive bone loss and may be at risk of osteoporosis. Opportunistic use of chest X-rays obtained for other indications could potentially be used to identify patients with signs of bone demineralization and at risk of osteoporosis in primary care settings particularly where DXA may not be readily available. We aimed at comparing the prevalence of bone demineralization using chest radiographs obtained for any indication in patients 50 to 65 years seen at an emergency department, as assessed from their radiology reports and by independent review by a radiologist. We also sought to explore clinical and demographic associates of low bone mass (LBM) among this population.

methodsWe conducted a cross-sectional review of electronic medical records of patients 50 to 65 years, who had obtained a chest X-ray at the emergency department of a large Level 1 trauma center in an urban teaching hospital between May 1, 2021, and May 31, 2021. We estimated the prevalence of "bone demineralization" from the X-rays reports and compared it with that obtained by an independent radiologist's review. We also used the 2020 US population census figures to estimate the number of people 50 to 65 years potentially at risk of LBM and investigated demographic and clinical correlates of LBM.

resultsWe reviewed 390 patient records, comprising 201 (51.5%) males and 189 (48.5%) females. Bone demineralization comment was found in 4 (1.0%) reports while radiologist review found 49 (12.6%). Applying sex-adjusted prevalence of 13.1% (using the direct method, with the 2020 US population as standard) to the 64.1 million adults 50 to 64 years in the US population, we estimated that approximately 8.4 million people will have bone demineralization in the population group. LBM was associated with hypertension in women (OR = 2.41, 95% CI = 1.03-5.64).

conclusionUse of opportunistic chest X-rays may be feasible in identifying patients at risk of bone loss outside the traditional screening age particularly in areas where DXA may not be readily available.

Indexed as

Mass ScreeningOsteoporosisRadiography, ThoracicAbsorptiometry, PhotonAgedBone DensityCross-Sectional StudiesEmergency Service, HospitalFemaleHumansMaleMiddle AgedPrevalenceRisk Factorsbone demineralizationchest X-rayslow bone massosteoporosis screening

Identifiers

PMID40657709
PMCPMC12264398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.