ArticleJournal of applied clinical medical physics2025
Enhancing inguinal tumor treatment outcomes with a customized 3D-printed bolus.
Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Evaluations of Penumbra Reduction Using Multi-Leaf Collimator and 3D Bolus in Scanned Proton Therapy.International journal of particle therapy · 2026Article
- A novel patient-specific solution for Merkel cell carcinoma in high-dose-rate brachytherapy.Journal of contemporary brachytherapy · 2026Article
- Enhancing inguinal tumor treatment outcomes with a customized 3D-printed bolus.Journal of applied clinical medical physics · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional boluses for pelvic lesions present challenges, including compromised skin dose coverage from large air gaps in treatment plans and increased uncertainties in treatment delivery due to variations in bolus fitting. This study evaluates the clinical benefits of a patient-specific, 3D-printed bolus (pBolus) in external beam radiation therapy (EBRT) for extramammary Paget's disease in the inguinal fold. A three-dimensional (3D) conformal plan utilizing the pBolus was compared to a conventional Superflab bolus (sBolus) under identical beam arrangements. The pBolus improved dose conformity by reducing air gaps in the treatment plan, and therefore, it was selected for clinical treatment. Weekly setup imaging revealed air gaps predominantly along the inguinal fold, demonstrating overall consistency in bolus fitting with minor air gap variations. Additionally, in vivo dosimetry confirmed dose accuracy. As a result, the patient achieved a favorable outcome, with no clinical evidence of disease at the follow-up visit.
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