Evidence map›Paper›PMID 40657671›Full record

ArticleJournal of applied clinical medical physics2025

Optimizing cardio-respiratory motion management in stereotactic arrhythmia radioablation through mid-position planning target volume.

Adèle Gabillaud, Louis Rigal, Raphaël Martins, Renaud De Crevoisier, Juan Cisneros, Loïg Duvergé, Mathieu Lederlin, Nolwenn Delaby, Karim Benali, Antoine Simon and 1 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adèle GabillaudDepartment of Medical Physics, CLCC Eugène Marquis, Rennes, France.
Louis RigalUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Raphaël MartinsUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Renaud De CrevoisierUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Juan CisnerosUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Loïg DuvergéDepartment of Radiation Oncology, CLCC Eugène Marquis, Rennes, France.
Mathieu LederlinUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Nolwenn DelabyDepartment of Medical Physics, CLCC Eugène Marquis, Rennes, France.
Karim BenaliDepartment of Cardiology, Saint-Etienne University Hospital, Saint-Priest-En-Jarez, France.
Antoine SimonUniv Rennes, CHU Rennes, CLCC Eugène Marquis, Inserm, Rennes, France.
Julien BellecDepartment of Medical Physics, CLCC Eugène Marquis, Rennes, France.

Funding

Fédération Française de Cardiologie, through the RADAR-CINETIC projectFrench National Research Association (ANR) ANR-11-LABX-0004
6 · The paper itself

Abstract

PURPOSE/

objectiveThis study proposes an implementation of the mid-position (MidP) approach to compensate for cardio-respiratory motions in the context of Stereotactic Arrhythmia Radioablation (STAR) and evaluates its benefits compared to an internal target volume (ITV) approach. MATERIALS AND

methodsFifteen patients who underwent STAR for refractory ventricular tachycardia in our institution were included in this retrospective planning study. For each patient, a cardiac-gated four-dimensional computed tomography (4D-CT

resultsCompared with the ITV method, the MidP approach resulted in a mean [min-max] relative PTV volume reduction of 30% [19%, 48%] (p < 0.001, Wilcoxon signed rank test). The mean [min-max] D95% CTV coverage was 105% [101%-114%] and 107% [101%-117%] of the prescription dose for MidP and ITV-based plans, respectively. The median dose to the whole heart was significantly lower with MidP-based plans with a mean difference of -0.5 Gy (p = 0.0084). The near-maximum dose (D1%) delivered to left coronary arteries, aorta, and stomach was systematically lower with the MidP-based plans.

conclusionCompared to ITV based approach, the use of MidP strategy for treatment planning of STAR leads to significantly smaller PTV and lower surrounding OAR doses while still achieving a clinically acceptable CTV coverage.

Indexed as

Arrhythmias, CardiacRadiosurgeryRadiotherapy Planning, Computer-AssistedTachycardia, VentricularAgedCone-Beam Computed TomographyFemaleFour-Dimensional Computed TomographyHumansMaleMiddle AgedMovementOrgans at RiskRadiotherapy DosageRadiotherapy, Intensity-ModulatedRespirationcardiac radioablationmid‐positionmotion managementstereotactic arrhythmia radioablation

Identifiers

PMID40657671
PMCPMC12257345

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.