Evidence map›Paper›PMID 40657628›Full record

ArticleGMS hygiene and infection control2025

Design of a multi-epitope vaccine candidate against Helicobacter pylori in gastric cancer: an immunoinformatic approach.

Ali Shojaeian, Samira Sanami, Shahab Mahmoudvand, Razieh Amini, Abbas Alibakhshi

Abstract read
In one paragraph

Article in GMS hygiene and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ali ShojaeianResearch Center for Molecular Medicine, Institute of Cancer, Avicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.
Samira SanamiAbnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Shahab MahmoudvandDepartment of Virology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Razieh AminiResearch Center for Molecular Medicine, Institute of Cancer, Avicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.
Abbas AlibakhshiResearch Center for Molecular Medicine, Institute of Cancer, Avicenna Health Research Institute, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric cancer and peptic ulcers can both be caused by Methods: This investigation chose two Results: The 3D structure of the multi-epitope vaccine was successfully predicted. The results of molecular docking analysis along with molecular dynamics (MD) simulation on the multi-epitope vaccine and immune receptors complex showed the structure has appropriate interaction energy between its two components and good stability. The vaccine candidate was cloned in silico in the pET28a (+) vector successfully in a suitable site. Conclusion: The results showed that final vaccine design would work well as an effective prophylactic vaccine against

Indexed as

BabAgastric cancerHelicobacter pylorimolecular dockingmolecular dynamicsmulti-epitope vaccineSabA

Identifiers

PMID40657628
PMCPMC12248002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.