Evidence map›Paper›PMID 40657497›Full record

ArticleFrontiers in microbiology2025

Enteroaggregative

Lu Liu, Shuang Wang, Xiaolin Yu, Yuzhen Chen, Yanru Chen, Gaoxiang Sun, Ziqing Liu, Lixiao Cheng, Huaning Zhang, Zengqiang Kou

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lu Liu *Infection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Shuang Wang *Infection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Xiaolin YuInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Yuzhen ChenInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Yanru ChenInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Gaoxiang SunInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Ziqing LiuInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Lixiao ChengInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Huaning ZhangInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.
Zengqiang KouInfection Disease Control of Institute, Shandong Center for Disease Control and Prevention, Jinan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Enteroaggregative Methods: This study presented a retrospective analysis of a foodborne diarrheal outbreak caused by EAEC in a county school in Shandong Province, China in 2023 by using epidemiological investigation and comprehensive genomic analysis techniques. Results: A total of 15 EAEC isolates were identified, including 13 from stool samples, one from sauced beef, and one from flies. Epidemiological and phylogenetic analyses pinpointed the EAEC isolates from sauced beef as the primary causative agent of the outbreak. Genomic comparisons revealed significant genetic consistency across nine outbreak-associated strains, particularly in virulence gene profiles, antimicrobial resistance gene profiles, molecular typing, and genetic evolution. Discussion: These findings underscored the utility of whole-genome sequencing in elucidating the genetic diversity of EAEC within specific environments and tracing its origins, thereby supporting targeted interventions such as infection control and prevention strategies. Notably, the study also identified an extensively drug-resistant (XDR) EAEC strain from flies in the canteen, harboring both the

Indexed as

antimicrobial resistanceEnteroaggregative Escherichia coli (EAEC)foodborne outbreaks“One Health” approachwhole-genome sequencing

Identifiers

PMID40657497
PMCPMC12245808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.