Evidence map›Paper›PMID 40657485›Full record

ArticleExplorations in economic history2025

Early-Life Lead Exposure and Male Longevity: Evidence from Historical Municipal Water Systems.

Jason Fletcher, Hamid Noghanibehambari

Abstract read
In one paragraph

Article in Explorations in economic history, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jason FletcherLa Follette School of Public Affairs, University of Wisconsin-Madison, 1225 Observatory Drive, Madison, WI 53706-1211, USA.
Hamid NoghanibehambariCollege of Business, Austin Peay State University, Marion St, Clarksville, TN 37040, USA.

Funding

Uncovering Life Course Constellations of Exposures through Big Data on Place, Time, and Family FactorsR01AG076830 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI Jason Michael Fletcher, JOSHUA R. GOLDSTEIN · 2022 to 2026
$2.9M
The Importance of Place in Determining Health and Mortality at Older AgesR01AG060109 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI FLETCHER, JASON MICHAEL, PALLONI, ALBERTO B. · 2018 to 2022
$2.2M
NIA NIH HHS R01 AG060109NIA NIH HHS R01 AG076830
6 · The paper itself

Abstract

Several research strands document the life-cycle impacts of lead exposure during early life. Yet little is known about the long-run effects of lead exposure during early life on old-age mortality outcomes. In this study, we employ Social Security Administration death records linked to the full-count 1940 census and document that birth-city lead status negatively affects later life old age longevity. These impacts are larger for cities with acidic water and older pipeline systems that allow higher lead levels to leach into drinking water. Further, we show that the impacts are almost exclusively concentrated on the lead status of the birth-city and not the city of residence later in life. An instrumental variable strategy suggests reductions in longevity associated with birth-city lead status of about 9.6 months. We also find education, socioeconomic standing, and income reductions during early adulthood as candidate mechanisms. Finally, we use WWII enlistment data and observe reductions in measures of cognitive ability among lead-exposed individuals.

Indexed as

Early-Life ExposuresHistorical DataI18In-Utero ExposuresJ18LeadLongevityMortalityN51N52O18Public HealthUrban InfrastructureWater Pollution

Identifiers

PMID40657485
PMCPMC12253308

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.