ArticleSultan Qaboos University medical journal2025
The Correlation Between Zinc Intake and Superoxide Dismutase Activity with Cognitive Function in the Elderly.
Article in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: This study aimed to analyse the correlation between zinc intake and superoxide dismutase (SOD) with cognitive function in the elderly. Thus, the role of zinc as a structural component of SOD, along with SOD's contribution to cognitive function, can be established. Methods: This cross-sectional study was conducted at Panti Sosial Tresna Wredha Budi Mulia 1 in Jakarta, Indonesia, from July to September 2024. Elderly men and women were included. Zinc intake was assessed using the Semi-Quantitative Food Frequency Questionnaire, while plasma SOD activity was measured by spectrophotometer. Cognitive function was assessed using the Montreal Cognitive Assessment-Indonesia version. Data were analysed using bivariate testing and multivariate linear regression. Results: A total of 85 subjects were included with a median age of 69 years (61.2% were female and 38.8% male). The majority (72.9%) had primary-level education and 87.1% had chronic diseases. The mean physical activity score was 75.4 ± 39.8, the mean body mass index was 21.8 ± 3.9 kg/m Conclusion: This study found no significant correlation between zinc intake and cognitive function. However, SOD activity were significantly correlated with cognitive function in the elderly.
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