Evidence map›Paper›PMID 40657422›Full record

ArticleNAR genomics and bioinformatics2025

Signal peptides restrict genome evolution and A-to-I RNA editing.

Yuange Duan, Shuxian Chen, Wanzhi Cai, Wen Song, Hu Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NAR genomics and bioinformatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuange DuanDepartment of Entomology and State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.ORCID https://orcid.org/0000-0003-2311-9859
Shuxian ChenDepartment of Entomology and State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Wanzhi CaiDepartment of Entomology and State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.
Wen SongState Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing 100193, China.ORCID https://orcid.org/0000-0002-9498-2409
Hu LiDepartment of Entomology and State Key Laboratory of Agricultural and Forestry Biosecurity, MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection, China Agricultural University, Beijing 100193, China.ORCID https://orcid.org/0000-0001-8590-1753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The genetic information flows from DNA to RNA to protein with high fidelity. While highly essential or conserved genomic sequences are often thought to be compensated by post-transcriptional mechanisms such as alternative splicing (AS) and RNA editing to enhance molecular diversity, this pattern does not necessarily hold true across all genomic regions. Signal peptides are short N-terminal sequences that direct the localization of proteins. By analyzing the genomes and transcriptomes of

Indexed as

Evolution, MolecularProtein Sorting SignalsRNA EditingAlternative SplicingAnimalsDrosophila melanogasterGenomeGenome, InsectHumansTranscriptomeProtein Sorting Signals

Identifiers

PMID40657422
PMCPMC12246783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.