Evidence map›Paper›PMID 40657276›Full record

ArticleInfection and drug resistance2025

Prevalence, Etiological Patterns and Factors Associated with Bacteraemia Among Febrile Children with Sickle Cell Anaemia in Jinja Regional Referral Hospital, Uganda.

Abdifatah Muhuyadin Haji Ali, Awil Abdulkadir Abdi, Amatarahman Ibrahim Said, Abdirizak Mohamed Omar, Abdirahman Hassan Salad, Faith Namukasa, Grace Ndeezi, Martin Nduwimana

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Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Abdifatah Muhuyadin Haji AliDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.ORCID 0009-0002-3656-5989
Awil Abdulkadir AbdiDepartment of Internal Medicine, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.ORCID 0009-0001-1983-3470
Amatarahman Ibrahim SaidDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.
Abdirizak Mohamed OmarDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.
Abdirahman Hassan SaladDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.
Faith NamukasaDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.
Grace NdeeziDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.
Martin NduwimanaDepartment of Pediatrics, Faculty of Clinical Medicine and Dentistry, Kampala International University, Bushenyi, Uganda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Children with sickle cell anemia (SCA) are highly susceptible to bacterial infections. While studies in Sub-Saharan Africa have explored the prevalence and causes of bacteremia in SCA, no such data exist from Uganda. This study aimed to determine the prevalence, bacterial causes, and associated factors of bacteremia among febrile children with SCA at Jinja Regional Referral Hospital (JRRH). Methods: We conducted a cross-sectional study among febrile children ≤18 years with confirmed SCA at JRRH. Data on sociodemographic, clinical, and laboratory variables were collected from caregivers and medical records. Blood samples were cultured using the BACTEC FX200 system and sensitivity for Kirby-Bauer disk diffusion. Descriptive statistics reported prevalence and etiology. Binary logistic regression was used to identify factors associated with bacteraemia, using SPSS v26. Statistical significance was set at p < 0.05. Results: Of the 209 febrile children enrolled, 114 (54.5%) were male and 116 (55.5%) were under five years. Bacteremia was confirmed in 44 patients (21.1%). The most frequent isolate was Conclusion: Bacteremia was common among febrile children with SCA, with

Indexed as

bacteremiaEscherichia coliprevalencesickle cell anemiaStaphylococcus aureusUganda

Identifiers

PMID40657276
PMCPMC12248708

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